Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAI --- CAIX | 6,7-Dimethoxy-1-(4'-fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-sulfonamide | Drug Info |
| 5HT1a --- SERT | 1-(3-Benzo[b]thiophen-2-yl-8-aza-bicyclo[3.2.1]oct-8-yl)-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[4-(4,6-Dimethyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(Quinolin-5-yloxy)-ethyl]-piperidin-4-yloxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1b --- SERT | (2-(benzo[b]thiophen-3-yl)cyclopropyl)-N,N-dimethylmethanamine | Drug Info |
| AChE --- NMDA | N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propane-1,3-diamine | Drug Info |
| ADRA1A --- HRH1 | 2-((3-phenylimidazolidin-1-yl)methyl)piperidine | Drug Info |
| ADRA1A --- HRH1 | 8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | Drug Info |
| ADRA1A --- HRH1 | CHEMBL1178351 | Drug Info |
| ADRA1A --- HRH1 | Zonalon | Drug Info |
| CABL --- FGFR1 | Dasatinib | Drug Info |
| CAI --- CAIX | Imatinib | Drug Info |
| Aurora --- VEGFR | 7-(5-(3-(piperidin-1-yl)propoxy)-1H-indol-2-yl)isoindolin-1-one | Drug Info |
| AuroraA --- STK1 | N-(4-(4-methyl-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)propionamide | Drug Info |
| AuroraA --- STK1 | N-(4-(6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-2-ylamino)phenethyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | N-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-2,3-difluorophenyl-2-3-7-3-4-2-hydroxyethyl-piperazin-1-yl-propoxy-6-methoxyquinazolin-4-ylamino-1H-pyrazol-5-yl-acetamide | Drug Info |
| AuroraA --- STK1 | 4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[4-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine | Drug Info |
| AuroraA --- STK1 | 2-{2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}-N-(3-methoxyphenyl)acetamide | Drug Info |
| AuroraA --- STK1 | 1-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)-3-(tetrahydro-2H-pyran-4-yl)urea | Drug Info |
| AuroraA --- STK1 | 3-(1-methyl-1H-pyrazol-4-yl)-N-(4-methylthiophen-2-yl)imidazo[1,2-a]pyrazin-8-amine | Drug Info |
| B-Raf --- VEGFR | N5-(3-(9H-purin-6-yl)pyridin-2-yl)-N1-(4-chlorophenyl)-6-methylisoquinoline-1,5-diamine | Drug Info |
| Beta PDGFR --- CABL | N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-2-naphthamide | Drug Info |
| Beta PDGFR --- MCSF | CHEMBL475817 | Drug Info |
| BNOS --- Hepatocyte NOS | 6-Cyclohexylmethyl-piperidin-(2Z)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | SID7967944 | Drug Info |
| BNOS --- Hepatocyte NOS | 2-(2-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidin-1-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide | Drug Info |
| BNOS --- Hepatocyte NOS | 4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hydrochloride | Drug Info |
| BNOS --- Hepatocyte NOS | CHEMBL522771 | Drug Info |
| BNOS --- Hepatocyte NOS | 6-Propyl-piperidin-(2Z)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | N-(1-(2-(2-Hydroxyethylamino)ethyl)indolin-6-yl)thiophene-2-carboximidamide | Drug Info |
| BNOS --- Hepatocyte NOS | 5-Chloro-3-(4-methyl-piperazin-1-ylmethyl)-3H-benzooxazol-2-one | Drug Info |
| BNOS --- Hepatocyte NOS | 7,8-difluoro-4-(((2-fluorobenzyl)(pyrazin-2-yl)amino)methyl)quinolin-2(1H)-one | Drug Info |
| CAI --- CAIX | 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide | Drug Info |
| 5HT1a --- SERT | [3-(5-Fluoro-1H-indol-3-yl)-propyl]-[2-(quinolin-5-yloxy)-ethyl]-amine | Drug Info |
| 5HT1a --- SERT | (S)-1-[(4R,6R)-4-(5-Fluoro-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-(4-(benzo[b]thiophen-2-yl)piperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | [3-(1H-Indol-2-yl)-propyl]-[2-(2-methoxy-phenoxy)-ethyl]-amine | Drug Info |
| 5LOX --- HRH1 | (5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-furan-2-ylmethyl)-N-hydroxyurea | Drug Info |
| ADRA1A --- HRH1 | 4-[(4-Hydroxyphenyl)methyl]-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | Drug Info |
| ADRA1A --- HRH1 | 2-({(2R)-1-[4-(4-{[3-(Hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)-4-[(4-hydroxyphenyl)methyl]-1(2H)-phthalazinone | Drug Info |
| CABL --- Ckit | PD-0173956 | Drug Info |
| CABL --- MCSF | Sunitinib | Drug Info |
| CAI --- CAIX | Zonisamide | Drug Info |
| Aurora --- VEGFR | N-(4-(benzo[d]thiazol-2-yl)phenyl)-4-(4-methylpiperazin-1-yl)pyrimidin-2-amine | Drug Info |
| AuroraA --- STK1 | N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-((4-(methylsulfonyl)piperazin-1-yl)methyl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(3-(1H-pyrazol-4-yl)-6-(trifluoromethyl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-(piperidin-4-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | (Z)-5-(Indolin-1-ylsulfonyl)-3-{[3-(3-morpholino-3-oxopropyl)-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl]methylene}indolin-2-one | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.