Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Erbeta --- ER | [2-(4-Fluoro-phenyl)-6-hydroxy-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone; hydrochloride | Drug Info |
| MMP13 --- MMP1 | 4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide | Drug Info |
| Erbeta --- ER | 6-(3-hydroxyphenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)naphthalen-2-ol | Drug Info |
| MMP13 --- MMP1 | (3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfonyl)-tetrahydro-pyran-3-carboxylic acid hydroxyamide | Drug Info |
| Erbeta --- ER | 3-(3-Bromo-4-hydroxy-phenyl)-2-ethyl-2H-benzo[1,4]oxazine-5,7-diol | Drug Info |
| MMP13 --- MMP14 | rac-N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl)propan-2-yl)-N-hydroxyformamide | Drug Info |
| Erbeta --- ER | SID14732345 | Drug Info |
| PPAR gamma --- PPAR delta | 3-(4-((5-(4-tert-butylphenyl)-1,2,4-oxadiazol-3-yl)methoxy)phenyl)-2-isopropoxypropanoic acid | Drug Info |
| MMP13 --- MMP9 | N-Hydroxy-2-{methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-benzamide | Drug Info |
| Erbeta --- ER | 5-Amino-2-((2S,3R)-2-amino-3-hydroxy-butyrylamino)-pentanoic acid [(3S,6R,9S,12R,15R,18R,21R)-6,9,18-tris-(3-amino-propyl)-15-benzyl-3-((R)-1-hydroxy-ethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19heptaaza-cyclotetracos-21-yl]-amide | Drug Info |
| PPAR gamma --- PPAR delta | methyl 2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetate | Drug Info |
| MMP2 --- HER2 | (2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperidin-1-yl)ethyl)-2-(4-phenylpiperazine-1-carbonyl)piperidine-3-carboxamide | Drug Info |
| Erbeta --- ER | 5-[4-(2-Piperidin-1-yl-ethoxy)-phenyl]-5,6-dihydro-benzo[c]phenanthridine-2,8-diol | Drug Info |
| PR --- mRNA of AR | 2'-Hydroxy-3-methoxy-biphenyl-4-carbonitrile | Drug Info |
| MMP2 --- MMP1 | cyclopentylcarbamoylphosphonic acid | Drug Info |
| Erbeta --- Mcl1 | SID24275405 | Drug Info |
| PR --- mRNA of AR | Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-2,6-dimethylpyridine-3-carboxylate | Drug Info |
| MMP2 --- MMP13 | (2S,3R)-3-hydroxy-2-(4-(5-(4-(methylsulfonamido)benzofuran-2-carboxamido)pyridin-2-yl)phenylsulfonamido)butanoic acid | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-3-yl-ethanone | Drug Info |
| PR --- mRNA of AR | 1,6,8,8,9-Pentamethyl-4-trifluoromethyl-8,9-dihydro-1H-pyrido[3,2-g]quinolin-2-one | Drug Info |
| MMP2 --- MMP13 | (R)-N-hydroxy-3-methyl-2-(N-methylnaphthalene-2-sulfonamido)butanamide | Drug Info |
| Ftase --- FPTase | 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-ethoxy-pyridin-3-ylmethyl ester | Drug Info |
| PR --- mRNA of AR | 9-Fluoro-2,2,4-trimethyl-5-((Z)-3-methyl-but-2-enylidene)-2,5-dihydro-1H-6-oxa-1-aza-chrysene | Drug Info |
| MMP2 --- MMP13 | 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclopropylsulfonyl)-N-hydroxypiperidine-4-carboxamide | Drug Info |
| Ftase --- FPTase | (2S)-2-(2-(3-((1H-imidazol-5-yl)methyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)acetamido)-4-(methylthio)butanoic acid | Drug Info |
| PR --- mRNA of AR | 6,7,7,8,8-Pentamethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one | Drug Info |
| MMP2 --- MMP13 | (R)-2-(7-ethoxy-N-isopentylnaphthalene-2-sulfonamido)-N-hydroxy-3-methylbutanamide | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid (1-oxy-pyridin-3-yl)-amide | Drug Info |
| PR --- mRNA of AR | rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-m-tolylpropan-1-one | Drug Info |
| MMP2 --- MMP13 | N-hydroxy-2-(4-(4-(trifluoromethyl)phenoxy)piperidin-1-ylsulfonyl)benzamide | Drug Info |
| Ftase --- FPTase | 4-((1H-imidazol-1-yl)methyl)-2-(3-(2-oxoazepan-3-yl)phenoxy)benzonitrile | Drug Info |
| PR --- mRNA of AR | (2S)-2-ethyl-1,2,3,6-tetrahydro-1-(2,2,2-trifluoroethyl)-9-(trifluoromethyl)-7H-[1,4]oxazino[3,2-g]quinolin-7-one | Drug Info |
| MMP2 --- MMP13 | 2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benzamide | Drug Info |
| Ftase --- FPTase | (S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propionylamino]-3-methyl-butyrylamino}-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid | Drug Info |
| Renin --- Cathepsin D | 3-{2-[2-Benzyl-4-(4-methylamino-piperidin-1-yl)-4-oxo-butyrylamino]-3-methylsulfanyl-propionylamino}-4-cyclohexyl-2-hydroxy-butyric acid isopropyl ester (CP-108,671) | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-(2-carboxyethylamino)-3-cyclohexyl-1-oxopropan-2-yl)carbamoyl)-6-p-tolylhexanoic acid | Drug Info |
| Ftase --- FPTase | (S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethyl-3H-imidazol-4-yl)-acetylamino]-pentyl}-naphthalen-1-ylmethyl-amino)-acetylamino]-4-methylsulfanyl-butyric acid | Drug Info |
| S5AR --- SRD5A2 | (1S,9aR,11aS)-6-Chloro-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylic acid (2,5-bis-trifluoromethyl-phenyl)-amide | Drug Info |
| MMP2 --- MMP3 | 2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine-1-sulfonyl]-N-hydroxy-2-methyl-propionamide | Drug Info |
| Ftase --- FPTase | Pseudopeptide derivative | Drug Info |
| S5AR --- SRD5A2 | 7-Chloro-4a-methyl-3,4,4a,9-tetrahydro-phenanthrene-2-carboxylic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(3'-trifluoromethyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
| Ftase --- FPTase | SID146411 | Drug Info |
| S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-N-(2-tert-butylphenyl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-[4-(tetrahydro-furan-2-yl)-phenyl]-hexanoic acid | Drug Info |
| Ftase --- FPTase | C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-imidazo[1,2-a]quinolin-7-yl]-C-(3-methyl-3H-imidazol-4-yl)-methylamine | Drug Info |
| S5AR --- SRD5A2 | (10R,13S)-10,13-Dimethyl-4-trifluoromethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione | Drug Info |
| MMP-2 --- MMP-3 | (R)-N1-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylpropylamino)butan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide | Drug Info |
| Ftase --- FPTase | 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[2-(1-methyl-1H-imidazol-4-yl)-ethyl]-amide} | Drug Info |
| S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-N',N'-diphenyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carbohydrazide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.