Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CABL --- STK1 | PHA-739358 | Drug Info |
| Aurora --- GSK | 3-(4-(3-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamino)phenyl)propanoic acid | Drug Info |
| AuroraA --- ALK5 | 6-(2-Amino-6-methyl-4-pyrimidinyl)-1H-indazol-3-amine | Drug Info |
| AuroraA --- STK1 | 3-Chloro-N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)-pyridin-2-yloxy)phenyl)benzamide | Drug Info |
| AuroraA --- STK1 | 3-(((2S,5S)-2,5-dimethylmorpholino)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 4-Chloro-N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)-pyridin-2-yloxy)phenyl)benzamide | Drug Info |
| AuroraA --- STK1 | CHEMBL215022 | Drug Info |
| AuroraA --- STK1 | N-[3-[(3-Fluoro-1-azetidinyl)methyl]-5-isothiazolyl]-6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine Trifluoroacetate | Drug Info |
| AuroraA --- STK1 | 3-methyl-N-(3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 3-((1R,5S)-8-oxa-3-azabicyclo[3.2.1]octan-3-ylmethyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 4-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine | Drug Info |
| CDK1 --- Cyclin E | SNS-032 | Drug Info |
| Beta PDGFR --- Ckit | N,6-Dimethyl-7-(1-((S)-3-methylmorpholino)phthalazin-6-yl)-benzo[d]isoxazol-3-amine | Drug Info |
| BNOS --- Hepatocyte NOS | N-(3-Chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)isobutyramide | Drug Info |
| BNOS --- Hepatocyte NOS | (S)-4-chloro-2-((isobutyl(1-methylpiperidin-3-yl)amino)methyl)benzonitrile | Drug Info |
| BNOS --- Hepatocyte NOS | 4-((7-Chloro-2-cyclobutyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)-7,8-difluoroquinolin-2(1H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | 1-aminoisoquinoline | Drug Info |
| BNOS --- Hepatocyte NOS | 6-[4-(1-Methyl-pyrrolidin-3-yloxy)-naphthalen-1-yl]-pyridin-2-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | 6-isobutyl-4-methylpyridin-2-amine | Drug Info |
| BNOS --- Hepatocyte NOS | 2-Amino-N-(3-aminomethyl-phenyl)-acetamidine | Drug Info |
| BNOS --- Hepatocyte NOS | 4-chloro-2-((methyl(1-methylpiperidin-4-yl)amino)methyl)benzonitrile | Drug Info |
| BNOS --- Hepatocyte NOS | (S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-propionic acid | Drug Info |
| CABL --- PKCA | N-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)isonicotinamide | Drug Info |
| 5HT1a --- SERT | [3-(5-Fluoro-1H-indol-3-yl)-propyl]-[2-(1H-indol-4-yloxy)-ethyl]-amine | Drug Info |
| 5HT1a --- SERT | 3-{Cyclobutyl[3-(6-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-methoxyphenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | 1-(4-methoxyphenyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propan-1-one | Drug Info |
| 5LOX --- HRH1 | 1-(4-{4-[4-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidin-1-yl)butoxy]phenyl}but-3-yn-1-yl)-1-hydroxyurea | Drug Info |
| AChE --- NMDA | N-[3-(9H-Carbazol-4-yloxy)propyl]-N'-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propane-1,3-diamine | Drug Info |
| ADRA1A --- HRH1 | 2-{[(2R)-1-Methyl-2-pyrrolidinyl]methyl}-4-pentyl-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | (S)-2-({5-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanyl)-propyl]-4-methyl-thiophene-2-carbonyl}-amino)-pentanedioic acid | Drug Info |
| ADRA1A --- HRH1 | 4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one | Drug Info |
| CABL --- FGFR1 | MK-2461 | Drug Info |
| CABL --- VEGFR1 | Sorafenib | Drug Info |
| Aurora --- VEGFR | 7-(1H-pyrrol-2-yl)isoindolin-1-one | Drug Info |
| AuroraA --- CDK4 | 4-[4-({7-cyclohexyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}amino)phenyl]-1,4-thiomorpholine-1,1-dione | Drug Info |
| AuroraA --- STK1 | N-(2-(2-(3-(trifluoromethyl)phenylamino)-1H-benzo[d]imidazol-6-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | 3-isopropyl-N-(3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 3-((3,3-dimethylmorpholino)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | TCMDC-134147 | Drug Info |
| AuroraA --- STK1 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-(piperazin-1-yl)pyrimidin-2-ylthio)phenyl)propionamide | Drug Info |
| AuroraA --- STK1 | N-(pyridin-2-ylmethyl)-6-(pyrrolidin-1-yl)-3-styryl-1H-indazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-{4-[1-[2-(4-Morpholinyl)-2-oxoethyl]-4-(1H-pyrrolo[2,3-b]-pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}-N'-phenylurea | Drug Info |
| AuroraA --- STK1 | N-{4-[1-(2-Hydroxyethyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}-N'-phenylurea | Drug Info |
| Beta PDGFR --- CABL | N-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)cyclohexanecarboxamide | Drug Info |
| Beta PDGFR --- Ckit | 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid benzo[1,3]dioxol-5-ylamide | Drug Info |
| BNOS --- Hepatocyte NOS | 2-Methyl-[1,4]thiazepan-(5E)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | N-(3-Chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide | Drug Info |
| BNOS --- Hepatocyte NOS | 6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-1-yl]-pyridin-2-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | 5-Chloro-3-piperidin-1-ylmethyl-3H-benzooxazol-2-one | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.