Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Erbeta --- ER | 3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-quinolin-7-ol | Drug Info |
| S5AR --- SRD5A2 | 17-(1H-Benzimidazol-1-yl)androsta-4,16-dien-3-one | Drug Info |
| MMP13 --- MMP1 | 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-dimethylamino-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide | Drug Info |
| Erbeta --- ER | 4,6-dibromo-2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-benzoyl-phenyl)-amide | Drug Info |
| MMP13 --- MMP14 | 5-Amino-3-[4-(2-chloro-phenoxy)-phenoxy]-3-(2-ethoxy-ethyl)-piperidine-2,4,6-trione | Drug Info |
| Erbeta --- ER | 2-(4-Hydroxy-phenyl)-4-methoxy-quinolin-6-ol | Drug Info |
| S5AR --- SRD5A2 | 8-methoxy-4a-methyl-3,4,4a,9-tetrahydrophenanthren-2-ylphosphonous acid | Drug Info |
| MMP13 --- MMP3 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylmethyl)-ethyl]-formamide | Drug Info |
| Erbeta --- ER | (2S,3R)-5-Fluoro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-methoxy-phenyl)-amide | Drug Info |
| MMP2 --- HER2 | (2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-2-(4-phenylpiperazine-1-carbonyl)piperidine-3-carboxamide | Drug Info |
| Erbeta --- ER | 11-((7S,13S,17S)-3,17-Dihydroxy-13-methyl-6-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-ylsulfanyl)-undecanoic acid butyl-methyl-amide | Drug Info |
| S5AR --- SRD5A2 | 4-(3-{4-[(R)-1-(4-Isobutyl-phenyl)-ethoxy]-benzoyl}-indol-1-yl)-butyric acid | Drug Info |
| MMP2 --- MMP1 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-(4'-methanesulfonyl-biphenyl-4-yloxymethyl)-ethyl]-N-hydroxy-formamide | Drug Info |
| Erbeta --- Mcl1 | SID4241330 | Drug Info |
| S5AR --- SRD5A2 | (4aR,10bR)-4,10b-Dimethyl-8-phenylethynyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one | Drug Info |
| MMP2 --- MMP13 | (S)-3-Methyl-2-{4'-[(3-phenyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-butyric acid | Drug Info |
| Ftase --- FPTase | 4-(5-{[3-(2-Chloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile | Drug Info |
| S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-6-bromo-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
| MMP2 --- MMP13 | (R)-N-hydroxy-3-methyl-2-(naphthalene-2-sulfonamido)butanamide | Drug Info |
| Ftase --- FPTase | (S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-benzoylamino]-4-methylsulfanyl-butyric acid methyl ester | Drug Info |
| S5AR --- SRD5A2 | (1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylic acid diethylamide | Drug Info |
| MMP2 --- MMP13 | (S)-2-{4'-[(5-Ethyl-4-isopropoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid | Drug Info |
| Ftase --- FPTase | (S)-3-Hydroxy-2-[(S)-2-((S)-2-{2-[hydroxy-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-phosphinoyloxy]-acetylamino}-3-methyl-butyrylamino)-4-methyl-pentanoylamino]-propionic acid | Drug Info |
| ABL --- Src | 4-(2,4-Dichloro-phenylamino)-6-methoxy-quinoline-3-carbonitrile | Drug Info |
| MMP2 --- MMP13 | (S)-2-(4'-(4-(3-methoxypropyl)-3-methylbenzofuran-2-carboxamido)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid | Drug Info |
| Ftase --- FPTase | 5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-2-oxo-1,2-dihydro-pyridine-3-carbonitrile | Drug Info |
| ABL --- Src | 4-(2,4-Dichloro-phenylamino)-6-methoxy-7-(1-methyl-piperidin-4-ylmethoxy)-quinoline-3-carbonitrile | Drug Info |
| MMP2 --- MMP13 | (S)-3-methyl-2-(4'-(3-methyl-4-phenoxybenzofuran-2-carboxamido)biphenyl-4-ylsulfonamido)butanoic acid | Drug Info |
| Ftase --- FPTase | 1-[(2R)-2-{[(4-cyanophenyl)methyl]amino}-3-(1-methyl-1H-imidazol-5-yl)propanoyl]-5-(naphthalen-1-yl)-1,2,3,6-tetrahydropyridine-4-carbonitrile | Drug Info |
| TEK --- BRaf | 4-(6-Methyl-5-(3-(6-(methylamino)pyrimidin-4-yl)pyridin-2-ylamino)isoquinolin-1-ylamino)benzonitrile | Drug Info |
| MMP2 --- MMP13 | N-hydroxy-1-isonicotinoyl-4-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)piperidine-4-carboxamide | Drug Info |
| Ftase --- FPTase | (+/-)-2-(3-(3-ethyl-1-methyl-2-oxoazepan-3-yl)phenoxy)-4-((1-methyl-1H-imidazol-5-yl)methyl)benzonitrile | Drug Info |
| TRIP5 --- mRNA of KIF11 | (+/-)-1-(3-Hydroxyphenyl)-2-(beta-aminopropionyl)-8-chloro-1,2,3,4-tetrahydro-beta-carboline hydrochloride | Drug Info |
| MMP2 --- MMP14 | 4'-O-Methylepigallocatechin-3-O-gallate | Drug Info |
| Ftase --- FPTase | (17R,20R)-19,20,21,22-Tetrahydro-21-methyl19-oxo-17H-15,17:18,20-diethano-6,10:12,16-dimetheno-16H-imidazo[3,4-h][1,8,11,14]oxatriazacycloeicosine-9-carbonitrile | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(4-chlorophenyl)-2,7,7-trimethyl-5-oxo-4-phenyl-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-[4'-(1H-tetrazol-5-yl)-biphenyl-4-yl]-hexanoic acid | Drug Info |
| Ftase --- FPTase | Pyridine-2-sulfonic acid [6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-thiophen-3-ylmethyl-amide | Drug Info |
| Ftase --- FPTase | 1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrole-3-carboxylic acid ethyl ester | Drug Info |
| TRIP5 --- mRNA of KIF11 | SID24831583 | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-6-(3',5'-dichloro-biphenyl-4-yl)-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
| Ftase --- FPTase | 1-[4-((R)-3,7-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone | Drug Info |
| TRIP5 --- mRNA of KIF11 | 2-(4'-Hydroxyphenyl)-3-benzyl-6-(4-methylpiperazin-1-yl)-1,4-dihydroquinoline-4-one | Drug Info |
| MMP2 --- MMP3 | (2R,3S)-N*4*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethyl-propyl]-2,N*1*-dihydroxy-3-(3-phenyl-propyl)-succinamide | Drug Info |
| Ftase --- FPTase | [((2E,6E,10E)-3,7,11,15-Tetramethyl-hexadeca-2,6,10,14-tetraenylcarbamoyl)-methyl]-phosphonic acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | 6-fluoro-2-methyl-9H-carbazole | Drug Info |
| MMP-2 --- MMP-3 | (R)-1-(1-(methylamino)-1-oxo-3-phenylpropan-2-yl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea | Drug Info |
| Ftase --- FPTase | N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)-4-methoxyquinoline-2-carboxamide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.