Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Erbeta --- ER | 2-hydroxy-4,7-dimethoxyphenanthrene | Drug Info |
| MMP1 --- MMP3 | (S)-2-[(R)-2-((R)-1-Hydroxy-1-hydroxycarbamoyl-ethyl)-5-phenyl-pentanoylamino]-3-phenyl-propionic acid | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aS)-7-(3,4-Dihydro-2H-quinoline-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one | Drug Info |
| Erbeta --- ER | (2S,3R)-2-{4-[2-((R)-3-Fluoro-pyrrolidin-1-yl)-ethoxy]-phenyl}-3-(4-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| MMP1 --- MMP9 | 1H-Benzotriazole-5-carboxylic acid [(R)-1-((S)-1-carbamoyl-2-pyridin-3-yl-ethylcarbamoyl)-2-mercapto-ethyl]-amide | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one | Drug Info |
| Erbeta --- ER | 4-bromo-2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol | Drug Info |
| MMP13 --- MMP1 | 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-sulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | 7-chloro-4a-methyl-3,4,4a,9-tetrahydrophenanthren-2-ylphosphonous acid | Drug Info |
| Erbeta --- ER | 3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid | Drug Info |
| MMP13 --- MMP1 | 1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cyclohexanecarboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | (8S,9S,10R,13S,14S,17S)-17-(diisopropylcarbamoyl)-10,13-dimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid | Drug Info |
| Erbeta --- ER | 2-Benzyl-4-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-ol | Drug Info |
| MMP13 --- MMP1 | 3-Hydroxy-4-(4-p-tolyloxy-benzenesulfonyl)-tetrahydro-pyran-3-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | 3-(17-Diisopropylcarbamoyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)-propionic acid | Drug Info |
| Erbeta --- ER | [2-(4-{1-[4-(2-Diisopropylamino-ethoxy)-phenyl]-3-methyl-but-1-enyl}-phenoxy)-ethyl]-diisopropyl-amine | Drug Info |
| MMP13 --- MMP1 | 4-(2-Amino-acetyl)-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | 4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylic acid p-tolyl ester | Drug Info |
| Erbeta --- ER | (2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol | Drug Info |
| MMP13 --- MMP1 | (2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide | Drug Info |
| ABL --- Src | (2,4-Dichloro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-amine | Drug Info |
| Erbeta --- ER | 7-butyl-2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | Drug Info |
| MMP13 --- MMP14 | 5-Amino-3-(2-ethoxy-ethyl)-3-{4-[4-(1H-pyrazol-4-yl)-phenoxy]-phenoxy}-piperidine-2,4,6-trione | Drug Info |
| ABL --- Src | (4-tert-Butoxy-3,5-dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-amine | Drug Info |
| Erbeta --- ER | 3-(4-(3-butyl-2-phenylnaphthalen-1-yloxy)phenyl)acrylic acid | Drug Info |
| MMP13 --- MMP3 | 3-{1-[(Methoxy-phenyl-methyl)-carbamoyl]-2,2-dimethyl-propylcarbamoyl}-6-(2-methyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
| FGFR --- Src | N-{6-(2,6-Dichloro-phenyl)-2-[3-(4-methyl-piperazin-1-yl)-propylamino]-pyrido[2,3-d]pyrimidin-7-yl}-3,3-dimethyl-butyramide | Drug Info |
| Erbeta --- ER | (S)-1-(4-(2-(pyrrolidin-1-yl)propoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol | Drug Info |
| MMP13 --- MMP9 | 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiazol-2-ylmethoxy)-biphenyl-4-sulfonyl]-amino}-benzamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 2-(trifluoromethyl)-9H-carbazole | Drug Info |
| Erbeta --- ER | (2S,3R)-3-(4-hydroxyphenyl)-2-(4-((S)-2-(pyrrolidin-1-yl)butoxy)phenyl)-2,3-dihydrobenzo[b][1,4]oxathiin-6-ol | Drug Info |
| MMP2 --- MMP1 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-(4'-ethoxy-biphenyl-4-yloxymethyl)-ethyl]-N-hydroxy-formamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N,N-diethyl-2-(thiophene-2-carboxamido)-5,7-dihydro-4H-thieno[2,3-c]thiopyran-3-carboxamide | Drug Info |
| Erbeta --- Mcl1 | SID7975783 | Drug Info |
| MMP2 --- MMP13 | N-Hydroxy-2-{1-isobutyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-3-yl}-acetamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | (+/-)-6-Methyl-1-(indol-3-yl)-2-butyryl-1,2,3,4-tetrahydro-beta-carboline | Drug Info |
| Ftase --- FPTase | [1-(3H-Imidazol-4-ylmethyl)-4-phenyl-1H-pyrrol-3-yl]-phenyl-methanone | Drug Info |
| MMP2 --- MMP13 | N-hydroxy-4-(4-(4-o-tolylpiperidin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-[3-Chloro-4'-(trifluoromethyl)-4-biphenylyl]sulfamide | Drug Info |
| Ftase --- FPTase | CHEMBL2365012 | Drug Info |
| MMP2 --- MMP13 | 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5-dichlorothiophen-3-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| Ftase --- FPTase | 5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-2-oxo-1-propyl-1,2-dihydro-pyridine-3-carbonitrile | Drug Info |
| MMP2 --- MMP13 | 2-(Biphenyl-4-sulfonylamino)-6-pyrrolidin-1-yl-hex-4-ynoic acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | 5-fluoro-2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-6-carboxamide | Drug Info |
| Ftase --- FPTase | (S)-2-[7-((R)-2-Amino-3-mercapto-propionylamino)-heptanoylamino]-4-methylsulfanyl-butyric acid | Drug Info |
| MMP2 --- MMP13 | (S)-2-{4'-[(5-Hydroxymethyl-4-methoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | 3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide | Drug Info |
| Ftase --- FPTase | 6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imidazol-4-yl)-prop-1-ynyl]-3''-methoxy-biphenyl-3-carbonitrile | Drug Info |
| MMP2 --- MMP13 | (3S)-4-{[4-(but-2-ynylamino)phenyl]sulfonyl}-Nhydroxy-2,2-dimethylthio-morpholine-3-carboxamide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.