Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Ftase --- FPTase | 1-(3-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one | Drug Info |
| MMP2 --- MMP13 | N-Hydroxy-2-(4-phenyl-piperidine-1-sulfonyl)-benzamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 1-(1-(2,5-difluorophenyl)-4-(3-morpholinopropyl)-4-phenyl-4,5-dihydro-1H-pyrazol-3-yl)ethanone | Drug Info |
| Ftase --- FPTase | [1-(3H-Imidazol-4-ylmethyl)-3-methyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone | Drug Info |
| MMP2 --- MMP13 | 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclopentylsulfonyl)-N-hydroxypiperidine-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | (+/-)-1-(4-(2,5-difluorophenyl)-2-phenyl-2H-pyrrol-1(5H)-yl)ethanone | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone | Drug Info |
| MMP2 --- MMP13 | N-[1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-1-phenyl-ethyl]-benzamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(3-aminopropyl)-N-(1-(3-benzyl-6-chloro-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)propyl)-4-methylbenzamide | Drug Info |
| Ftase --- FPTase | (+)1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone | Drug Info |
| MMP2 --- MMP13 | N-hydroxy-N-(4-((4-(2-methyl-4-(methylsulfonyl)phenethyl)piperidin-1-ylsulfonyl)methyl)tetrahydro-2H-pyran-4-yl)formamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | (+/-)-1-(3-Hydroxyphenyl)-2-butyryl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-piperidin-4-ylmethyl-piperidine-1-carboxamidine | Drug Info |
| MMP2 --- MMP13 | 1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 3-fluoro-4'-(methylsulfonyl)-4-(trifluoromethyl)biphenyl | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-phenyl-propan-1-one | Drug Info |
| MMP2 --- MMP3 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-4-(3-methoxy-phenyl)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-butyl]-phosphinic acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | tert-butyl 3-(N-(1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)propyl)-4-methylbenzamido)propylcarbamate | Drug Info |
| Ftase --- FPTase | 6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3'-ethoxy-biphenyl-3-carbonitrile | Drug Info |
| MMP2 --- MMP3 | (4-Benzoylamino-butyl)-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | (3aS,10R)-2-(5-amino-pentyl)-10-(3-hydroxy-phenyl)-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione | Drug Info |
| Ftase --- FPTase | 3-(3-(1H-imidazol-1-yl)propyl)-1-(4-phenoxybenzyl)-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione | Drug Info |
| MMP2 --- MMP3 | 4'-[(3R,5S)-5-Carboxy-3-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-nonyl]-biphenyl-4-carboxylic acid methyl ester | Drug Info |
| TRIP5 --- mRNA of KIF11 | 1-[(3R,3aR)-8-chloro-3-(3-dimethylamino-propyl)-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl]-ethanone | Drug Info |
| Ftase --- FPTase | N-[6-Cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-N-thiophen-3-ylmethyl-benzenesulfonamide | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxobutan-2-yl)carbamoyl)-6-phenylhexanoic acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(3-acetamidopropyl)-N-(1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)propyl)-4-methylbenzamide | Drug Info |
| Ftase --- FPTase | 4-{5-[(2-Cyclohexylmethyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile | Drug Info |
| MMP-2 --- MMP-3 | (R)-N4-hydroxy-N1-((S)-1-((R)-2-methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-yl)-2-(3-phenylpropyl)succinamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(2-methoxyphenyl)-2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide | Drug Info |
| Ftase --- FPTase | (S)-2-[(S)-2-((S)-2-{3-[Hydroxy-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-phosphinoyl]-propionylamino}-3-methyl-butyrylamino)-3-methyl-butyrylamino]-4-methylsulfanyl-butyric acid | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(2,5-dimethylfuran-3-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| TRIP5 --- mRNA of KIF11 | 3-(trifluoromethyl)-9H-carbazole | Drug Info |
| Ftase --- FPTase | 7-[Amino-(4-chloro-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-5-(3-chloro-phenyl)-1-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one | Drug Info |
| MMP2 --- MMP9 | 3-hydroxy-1-((4-(4-methoxyphenoxy)phenylsulfonyl)methyl)pyridin-2(1H)-one | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-[3-amino-4'-(trifluoromethyl)-4-biphenylyl]sulfamide | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyclohexyl methyl-N'-cyano-piperidine-1-carboxamidine | Drug Info |
| MMP2 --- MMP9 | N-hydroxy-3-(6-methoxy-2-oxo-2H-chromen-3-yl) | Drug Info |
| TRIP5 --- mRNA of KIF11 | O-(trityl)-L-serine | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-phenyl-ethanone | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(1-methyl-1H-indazole-3-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| Lck --- VEGFR | N-(2,3-dihydro-1H-inden-4-yl)-4-methyl-3-(2-(methylamino)quinazolin-6-yl)benzamide | Drug Info |
| Ftase --- FPTase | N-Cyclopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-3-ylmethyl-acetamide | Drug Info |
| MMP2 --- MMP9 | 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-methoxy-biphenyl-4-sulfonyl)-butyric acid | Drug Info |
| Src --- VEGFR | N*2*,N*7*-Bis-[3-(4-methyl-piperazin-1-yl)-propyl]-3-phenyl-[1,6]naphthyridine-2,7-diamine | Drug Info |
| Ftase --- FPTase | (S)-2-[2-({(S)-3-Methyl-2-[2-(3-nitro-benzylsulfanyl)-acetylamino]-pentyl}-naphthalen-1-ylmethyl-amino)-acetylamino]-4-methylsulfanyl-butyric acid | Drug Info |
| MMP2 --- MMP9 | (S)-N-hydroxy-2-(pyridin-3-ylmethylamino)-3-(N-(4-(p-tolyloxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| VEGFR1 --- FGFR1 | 4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one | Drug Info |
| Ftase --- FPTase | 4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-sulfonic acid dimethylamide | Drug Info |
| MMP2 --- MMP9 | N-((3S)-3,4-dihydroxy-1-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)butan-2-yl)-N-hydroxyformamide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.