Target Pair Drug Name
Ftase --- FPTase 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-pyridin-4-yl-propan-1-one Drug Info
MMP2 --- MMP9 N-hydroxy-N-(5-morpholino-5-oxo-1-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)pentan-2-yl)formamide Drug Info
FGFR --- VEGFR N*7*-(4-Diethylamino-butyl)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridine-2,7-diamine Drug Info
Ftase --- FPTase (S)-2-({2'-Methyl-5-[2-((E)-4-propoxy-pyridin-3-yl)-vinyl]-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid Drug Info
MMP2 --- MMP9 N-hydroxy-N-(2-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)ethyl)formamide Drug Info
Src --- VEGFR N-(2-chloro-5-methoxyphenyl)-5-isopropoxy-7-(3-morpholinopropoxy)quinazolin-4-amine Drug Info
Ftase --- FPTase Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-1,3-dimethoxy-6b,10,10,12a-tetramethyl-3,6,6a,6b,7,8,9,10,10a,11,12,12a-dodecahydro-1H-2,13-dioxa-benzo[a]cyclopenta[h]anthracen-9-yl ester Drug Info
MMP2 --- MMP9 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-trifluoromethyl-biphenyl-4-sulfonyl)-butyric acid Drug Info
VEGFR1 --- FGFR1 2-(1H-indazol-3-yl)-5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazole Drug Info
Ftase --- FPTase 2-(3-Bromo-phenoxy)-4-imidazol-1-ylmethyl-benzonitrile Drug Info
MMP2 --- MMP9 N-hydroxy-2-(N-(4-phenoxyphenyl)methan-15-ylsulfonamido)acetamide Drug Info
VEGFR2 --- AuroraA 7-(5-(3-(4-hydroxypiperidin-1-yl)propoxy)-1H-indol-2-yl)isoindolin-1-one Drug Info
Ftase --- FPTase [[6-Cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-(pyridine-3-sulfonyl)-amino]-acetic acid tert-butyl ester Drug Info
MMP2 --- MMP9 5-(4-Phenoxyphenyl)-5-(4-(2-(2,3-dihydrobenzo[b]-[1,4]dioxine-6-sulfonamido)3-methylbutyryl)-1,4-diazepan-1-yl)-pyrimidine-2,4,6(1H,3H,5H)-trione Drug Info
VEGFR2 --- CDK1 2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyrimidin-2-ylamino)phenyl)ethanol Drug Info
Ftase --- FPTase 4-(5-{[2-(3,5-Difluoro-benzyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile Drug Info
MMP2 --- MMP9 (R)-3-Phenyl-2-[4-(2-p-tolyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid Drug Info
VEGFR2 --- CDK1 3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine Drug Info
Ftase --- FPTase 1-[(2R,3R)-3-(2-Chloro-6-fluoro-benzyloxy)-5-fluoro-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
MMP2 --- MMP9 2-(7-Benzyloxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide Drug Info
VEGFR2 --- Ckit (3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione Drug Info
Ftase --- FPTase 1-(3-Chloro-phenyl)-4-[3-(2-methoxy-4'-trifluoromethyl-biphenyl-4-ylmethyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one Drug Info
MMP2 --- MMP9 (R)-4-Amino-2-[(biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-butyramide Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino)methyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide Drug Info
Ftase --- FPTase 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-pyridin-3-yl-piperidine-1-carboxamidine Drug Info
MMP3 --- MMP8 4-Methoxy-benzenesulfonic acid 3-hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl ester Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Drug Info
Ftase --- FPTase 6-[(2'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile Drug Info
MMP3 --- MMP8 2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide Drug Info
VEGFR2 --- Cmet rac-N-(3-Fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl)-1-(2-hydroxypropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide Drug Info
Ftase --- FPTase 6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-5-(2,2-difluoro-benzo[1,3]dioxol-5-yl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile Drug Info
MMP9 --- MMP3 2-(1-Hydroxy-2-mercapto-ethyl)-nonanoic acid [(S)-3-methyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-butyl]-amide Drug Info
VEGFR2 --- CSrc 4-{1-[(Benzyloxy)methyl]-1H-indol-3-yl}-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one Drug Info
Ftase --- FPTase (S)-2-({5-[2-((E)-4-Methoxy-pyridin-3-yl)-vinyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid Drug Info
mTOR --- AKT N-(6-(6-Chloro-5-(3-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide Drug Info
VEGFR2 --- CSrc N-(4-methyl-3-(1-(6-(2-(pyrrolidin-2-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide Drug Info
Ftase --- FPTase (S)-2-[(5-{2-[(E)-4-(Hydroxy-phenyl-methyl)-pyridin-3-yl]-vinyl}-2'-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid Drug Info
mTOR --- PI3K delta 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea Drug Info
VEGFR2 --- CSrc [6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-(1-methyl-1H-indol-4-yl)-amine Drug Info
Ftase --- FPTase 1-[6-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
mTOR --- PI3K gamma (3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)piperidin-4-yl)-9H-purin-2-yl)phenyl)methanol Drug Info
VEGFR2 --- CSrc isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)-3-methylphenylcarbamate Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-3-trifluoromethyl-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone Drug Info
mTOR --- PI3K gamma 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(2-chloropyridin-4-yl)urea Drug Info
VEGFR2 --- FGFR1 1-(1-tert-Butyl-1H-pyrazol-4-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea Drug Info
Ftase --- FPTase (S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-2-naphthalen-1-yl-benzoylamino)-4-methyl-pentanoic acid Drug Info
mTOR --- PI3K gamma (3-(6-morpholino-9-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-9H-purin-2-yl)phenyl)methanol Drug Info
VEGFR2 --- FGFR1 N-[2-(3-tert-Butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-N-(3-hydroxy-propyl)-acetamide Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid adamantan-1-ylamide Drug Info
mTOR --- PI3K gamma methyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino}phenyl)-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate Drug Info

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