Target Pair Drug Name
Ftase --- FPTase 4'-(2-Amino-3-mercapto-propylamino)-2'-propoxy-biphenyl-3-carboxylic acid 13 (FTI-288) Drug Info
MMP2 --- MMP3 (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-[1,1';4',1'']terphenyl-4-yl-hexanoic acid Drug Info
TRIP5 --- mRNA of KIF11 1-[(3R,3aR)-8-fluoro-3-(3-hydroxy-propyl)-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl]-ethanone Drug Info
Ftase --- FPTase 2-[4-((R)-2-Amino-3-mercapto-propylamino)-2-naphthalen-1-yl-benzoylamino]-4-methyl-pentanoic acid Drug Info
MMP2 --- MMP3 2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-N-hydroxy-acetamide Drug Info
TRIP5 --- mRNA of KIF11 2-(3'-Hydroxyphenyl)-3-benzyl-6-(morphilin-4-yl)-1,4-dihydroquinoline-4-one Drug Info
Ftase --- FPTase 1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-[1-(2-morpholin-4-yl-2-oxo-ethyl)-piperidin-4-yl]-ethanone Drug Info
MMP2 --- MMP3 (R)-3-(((S)-3-cyclohexyl-1-oxo-1-(phenethylamino)propan-2-yl)carbamoyl)-6-p-tolylhexanoic acid Drug Info
TRIP5 --- mRNA of KIF11 N-(3-aminopropyl)-4-methyl-N-(1-(4-oxo-3-(pyridin-2-ylmethyl)-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)propyl)benzamide Drug Info
Ftase --- FPTase [2-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylcarbamoyl)-ethyl]-phosphonic acid Drug Info
MMP2 --- MMP3 (R)-3-(((S)-3-cyclohexyl-1-(3-methoxy-3-oxopropylamino)-1-oxopropan-2-yl)carbamoyl)-6-p-tolylhexanoic acid Drug Info
TRIP5 --- mRNA of KIF11 1-{(3R,3aR)-3-[3-(4-acetyl-piperazin-1-yl)-propyl]-8-fluoro-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl}-ethanone Drug Info
Ftase --- FPTase 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-(4-trifluoromethoxy-phenyl)-piperidine-1-carboxamidine Drug Info
MMP2 --- MMP9 3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylsulfamoyl]-5-phenyl-pentanoic acid Drug Info
TRIP5 --- mRNA of KIF11 (+/-)-6-Chloro-1-(3-hydroxyphenyl)-2-propyl-1,2,3,4-tetrahydro-beta-carboline Drug Info
Ftase --- FPTase (S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-naphthalene-1-carbonyl]-amino}-4-methylsulfanyl-butyric acid methyl ester Drug Info
MMP2 --- MMP9 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-isopropyl-biphenyl-4-sulfonyl)-butyric acid Drug Info
TRIP5 --- mRNA of KIF11 4-(trifluoromethyl)biphenyl Drug Info
Ftase --- FPTase N-[6-Cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-N-thiophen-3-ylmethyl-benzenesulfonamide Drug Info
MMP2 --- MMP9 N-Hydroxy-2-{4-[5-(4-methoxy-phenyl)-oxazol-2-yl]-benzenesulfonylamino}-3-methyl-butyramide Drug Info
TRIP5 --- mRNA of KIF11 (R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)methylthio)propanoic acid Drug Info
Ftase --- FPTase 4-(2,3-dihydroxypropyl)-23-oxo-8-oxa-1,15,17,21-tetraazapentacyclo[19.2.2.13,7.19,13.015,19]heptacosa-3(27),4,6,9(26),10,12,16,18-octaen-10-yl cyanide Drug Info
MMP2 --- MMP9 5-(4-Phenoxyphenyl)-5-(4-(3-(N-(5-methylisoxazol-3-yl)sulfamoyl)benzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione Drug Info
TRIP5 --- mRNA of KIF11 N-(3-aminopropyl)-N-(1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)propyl)-2-chlorobenzamide Drug Info
Ftase --- FPTase 2-[3-(3-Ethyl-1-methyl-2-oxo-azepan-3-yl)-phenoxy]-4-imidazol-1-ylmethyl-benzonitrile Drug Info
MMP2 --- MMP9 11-(2',6'-Difluoro-biphenyl-4-ylmethyl)-2,10-dioxo-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide] Drug Info
Src --- VEGFR CHEMBL216105 Drug Info
Ftase --- FPTase (S)-2-[((S)-2-{(S)-2-[(S)-2-((R)-2,6-Diamino-hexanoylamino)-2-mercapto-acetylamino]-3-methyl-butyryl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-4-methylsulfanyl-butyric acid Drug Info
MMP2 --- MMP9 5-(4-Phenoxyphenyl)-5-(4-((8-(dimethylamino)napththalen-4-yl)sulfonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione Drug Info
VEGFR1 --- FGFR1 7-amino-6-(1H-benzo[d]imidazol-2-yl)-3H-imidazo[4,5-b]pyridin-5(4H)-one Drug Info
Ftase --- FPTase 1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-5-fluoro-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
MMP2 --- MMP9 (R)-2-[5-(4-Butoxy-phenylethynyl)-thiophene-2-sulfonylamino]-3-(1H-indol-3-yl)-propionic acid Drug Info
VEGFR2 --- AuroraA 5-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)vinyl)nicotinonitrile Drug Info
Ftase --- FPTase 4-(5-{[2-(3-Methoxy-phenyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile Drug Info
MMP2 --- MMP9 N-Hydroxy-2-{3-methyl-3-[4-(4-nitro-benzyloxy)-phenyl]-2-oxo-pyrrolidin-1-yl}-propionamide Drug Info
VEGFR2 --- CD135 N-{4-[3-amino-1-(2-hydroxyethyl)-1H-indazol-4-yl]phenyl}-N'-(3-methylphenyl)urea Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-2-methyl-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-ethoxy-benzyl ester Drug Info
MMP2 --- MMP9 (S)-2-Amino-N-hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-acetamide Drug Info
VEGFR2 --- CDK1 5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenyl)pyrimidin-2-amine Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-3-nitro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone Drug Info
MMP2 --- MMP9 (3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-phenylcarbamoyl]-piperidine-1-carboxylic acid methyl ester Drug Info
VEGFR2 --- CDK2 2-Oxo-3-[1-(4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrol-1-yl)-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-5-sulfonic acid amide Drug Info
MMP2 --- MMP9 (2S)-2,6-diamino-N-(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl)hexanamide Drug Info
VEGFR2 --- Ckit 1-cyclohexyl-3-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea Drug Info
Ftase --- FPTase (4-Bromo-phenyl)-[1-(3H-imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-methanone Drug Info
MMP3 --- MMP8 2-Benzenesulfonyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamoyl)-2-phenylacetamide Drug Info
Ftase --- FPTase 15,16-dibenzyl-17-oxo-(16R)-2-oxa-9,11,15,18-tetraazapentacyclo[17.6.2.13,7.09,13.023,27]octacosa-1(26),3,5,7(28),10,12,19(27),20,22,24-decaen-4-yl cyanide Drug Info
MMP3 --- MMP8 (S)-N-[3-Hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-3-phenylacetylamino-succinamic acid tert-butyl ester Drug Info
VEGFR2 --- Cmet 3-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenylamino)-4,4,4-trifluoro-N-phenylbutanamide Drug Info

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