Multi-target agents
Target Pair | Drug Name | |
---|---|---|
MMP13 --- MMP1 | 4-(4-Phenoxy-benzenesulfonylamino)-tetrahydro-pyran-4-carboxylic acid hydroxyamide | Drug Info |
S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-5-cyano-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
Erbeta --- ER | 8-Bromo-7-hydroxy-3-(4-hydroxy-phenyl)-naphthalene-1-carbonitrile | Drug Info |
MMP13 --- MMP1 | 8-bromo-4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxyquinoline-3-carboxamide | Drug Info |
S5AR --- SRD5A2 | (1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylic acid (2,5-bis-trifluoromethyl-phenyl)-amide | Drug Info |
Erbeta --- ER | 1-Ethyl-2-(4-hydroxy-phenyl)-3H-inden-5-ol | Drug Info |
MMP13 --- MMP1 | (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-6-(2-hydroxyethyl)-2,2-dimethylthiomorpholine-3-carboxamide | Drug Info |
S5AR --- SRD5A2 | (1S,9aR,11aS)-6-Dimethylaminomethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylic acid diethylamide | Drug Info |
Erbeta --- ER | rac-9a-ethyl-6-methyl-9,9a-dihydroindeno[2,1-e]indazole-7,10(3H,8H)-dione | Drug Info |
MMP13 --- MMP1 | 4-[4-(4-Cyano-phenoxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide | Drug Info |
ABL --- Src | 6-Methoxy-7-(1-methyl-piperidin-4-ylmethoxy)-4-(3,4,5-trimethoxy-phenylamino)-quinoline-3-carbonitrile | Drug Info |
Erbeta --- ER | 2-(3-butoxy-4-hydroxyphenyl)benzo[d]oxazol-6-ol | Drug Info |
MMP13 --- MMP14 | 5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-2-yl-phenoxy)-phenoxy]-piperidine-2,4,6-trione | Drug Info |
ABL --- Src | 4-(2-Bromo-4-chloro-5-methoxy-phenylamino)-6,7-dimethoxy-quinoline-3-carbonitrile | Drug Info |
Erbeta --- ER | 4-[6-(Isobutyl-methyl-amino)-4-phenyl-pyridin-2-yl]-phenol | Drug Info |
MMP13 --- MMP9 | 5-Bromo-2-({4-[4-(3-dimethylamino-propylamino)-but-2-ynyloxy]-benzenesulfonyl}-methyl-amino)-N-hydroxy-3-methyl-benzamide | Drug Info |
Lck --- Src | 5-(4-Phenoxy-phenyl)-7-(4-piperidin-1-yl-cyclohexyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | Drug Info |
Erbeta --- ER | (S)-5-[3-(2-Piperidin-1-yl-ethoxy)-phenyl]-11,12-dihydro-5H-6,13-dioxa-benzo[3,4]cyclohepta[1,2-a]naphthalene-2,8-diol | Drug Info |
MMP2 --- HER2 | (1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl)cyclohexanecarboxamide | Drug Info |
TRIP5 --- mRNA of KIF11 | (DL)-3-fluoro-4'-(methylsulfinyl)-4-(trifluoromethyl)biphenyl | Drug Info |
Erbeta --- ER | 4-bromo-2-(3-fluoro-4-hydroxyphenyl)-7-methoxybenzo[d]oxazol-5-ol | Drug Info |
MMP2 --- MMP1 | (S)-N-hydroxy-2,2-dimethyl-4-(4-(3,4,5-trimethoxyphenoxy)phenylsulfonyl)thiomorpholine-3-carboxamide | Drug Info |
TRIP5 --- mRNA of KIF11 | N-(3-aminopropyl)-N-(1-(5-benzyl-3-methyl-4-oxo-4,5-dihydroisoxazolo[5,4-d]pyrimidin-6-yl)propyl)-4-methylbenzamide | Drug Info |
Erbeta --- Mcl1 | SID24840723 | Drug Info |
MMP2 --- MMP13 | 2-(Biphenyl-4-sulfonylamino)-6-morpholin-4-yl-hex-4-ynoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | 2-(1,1,2-triphenylethylthio)ethanamine | Drug Info |
Ftase --- FPTase | 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-(3-hydroxy-phenylethynyl)-benzonitrile | Drug Info |
MMP2 --- MMP13 | (R)-N-hydroxy-2-(N-isopentylquinoline-2-sulfonamido)-3-methylbutanamide | Drug Info |
TRIP5 --- mRNA of KIF11 | (S)-1-(4-(2,5-difluorophenyl)-2-(3-hydroxyphenyl)-2H-pyrrol-1(5H)-yl)-2,2-dimethylpropan-1-one | Drug Info |
Ftase --- FPTase | (4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a]quinazolin-7-yl)(1-methyl-1H-imidazol-5-yl)methanamine | Drug Info |
MMP2 --- MMP13 | (R)-N-hydroxy-2-(N-isopentylnaphthalene-2-sulfonamido)-4-phenylbutanamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 2-acetyl-4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester | Drug Info |
Ftase --- FPTase | (S)-2-[(5-{2-[(E)-4-(Cyclohexyl-hydroxy-methyl)-pyridin-3-yl]-vinyl}-2'-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid | Drug Info |
MMP2 --- MMP13 | (R)-2-(N-benzylnaphthalene-2-sulfonamido)-N-hydroxy-3-methylbutanamide | Drug Info |
TRIP5 --- mRNA of KIF11 | N,N-diethyl-2-(thiophene-4-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide | Drug Info |
Ftase --- FPTase | (S)-3-Hydroxy-2-{(S)-2-[(S)-2-(3-mercapto-propionylamino)-3-methyl-butyrylamino]-4-methyl-pentanoylamino}-propionic acid | Drug Info |
MMP2 --- MMP13 | 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-4-yl)piperidine-4-carboxamide | Drug Info |
TRIP5 --- mRNA of KIF11 | N-(4-(3-(2,5-difluorophenyl)-1-(ethylcarbamoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-5-yl)butyl)-1H-imidazole-4-carboxamide | Drug Info |
Ftase --- FPTase | 4-(5-{[2-(2,4-Dichloro-benzyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile | Drug Info |
MMP2 --- MMP13 | N-hydroxy-4-(4-(4-(4-(pyridin-4-yl)piperazine-1-carbonyl)piperidin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 8-(Trifluoromethyl)-3,4-dihydro-1H-pyrido[3,2-b]carbazol-2(6H)-one | Drug Info |
Ftase --- FPTase | Lonafarnib | Drug Info |
MMP2 --- MMP3 | (R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-phenyl-propylamino]-octanoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | N-[7-(Trifluoromethyl)-9H-carbazol-2-yl]urea | Drug Info |
Ftase --- FPTase | 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-pentanoyl-piperazine-2-carboxylic acid pyrazin-2-ylamide | Drug Info |
MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(4'-methanesulfonyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | CHEMBL1829408 | Drug Info |
Ftase --- FPTase | (R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3,3-dimethyl-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-4-dimethylcarbamoyl-butyric acid | Drug Info |
MMP2 --- MMP3 | (2S,4R)-6-Biphenyl-3-yl-2-butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | 4-(3-hydroxyphenyl)-8-methoxy-N,N-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxamide | Drug Info |
Pagination
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