Multi-target agents

Target Pair Drug Name
JNK1 --- JNK3 N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(cyclopropylamino)picolinamide Drug Info
Erbeta --- ER (2S,3R)-2-[3-Bromo-4-(2-piperidin-1-yl-ethoxy)-phenyl]-3-(3-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]dithiin-6-ol Drug Info
JNK1 --- JNK3 2-(5-chloro-2-(4-methoxyphenoxy)pyridin-4-ylamino)-N-methylbenzamide Drug Info
PPAR gamma --- PPAR delta 2-isopropoxy-3-(4-((5-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-3-yl)methoxy)phenyl)propanoic acid Drug Info
Erbeta --- ER (2S,3R)-2-[3-Bromo-4-(2-piperidin-1-yl-ethoxy)-phenyl]-3-(4-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]dithiin-6-ol Drug Info
JNK1 --- JNK3 3-(2-(cyclopropylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazol-5(4H)-one Drug Info
PPAR gamma --- PPAR delta 2-(4-((4-(4-(N-Isopropyl-N-methyl)benzamide)-5-(4-(trifluoromethoxy)phenyl)thiazol-2-yl)methoxy)-2-methylphenoxy)acetic Acid Drug Info
Erbeta --- ER (R)-2-(1-(4-(3-(piperidin-1-yl)propoxy)benzyl)-2-phenyl-1H-indol-3-yl)-N-(4-(4-hydroxyphenyl)butan-2-yl)acetamide Drug Info
JNK1 --- JNK3 4-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-benzoic acid Drug Info
PR --- mRNA of AR rac-3-(3-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-tolylpropan-1-one Drug Info
Erbeta --- ER broussonin A Drug Info
MEP --- Cathepsin B 1-(1-(3,5-dichlorophenyl)-3-phenylpropylidene)thiosemicarbazide Drug Info
PR --- mRNA of AR 1-Nitro-4-(4,6,6-trimethyl-2-methylene-cyclohex-3-enylmethyl)-benzene Drug Info
Erbeta --- ER 3-(5-bromo-6-hydroxynaphthalen-2-yl)benzo[d]isoxazol-6-ol Drug Info
MEP --- Cathepsin B {(S)-1-[2,5-Dioxo-1-(3-phenyl-propyl)-piperidin-4-ylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester Drug Info
PR --- mRNA of AR 4-[1-(4-Fluorophenyl)-1H-indazol-5-yl]-N-(2-methylpropyl)-3-(trifluoromethyl)benzenesulfonamide Drug Info
Erbeta --- ER 8-Chloro-6-(4-hydroxy-phenyl)-naphthalen-2-ol Drug Info
MEP --- Cathepsin B 2-(p-tolyl(3-(trifluoromethyl)phenyl)methylene)hydrazinecarbothioamide Drug Info
PR --- mRNA of AR 9-bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline Drug Info
Erbeta --- ER (2-Cyclopentyl-6-hydroxy-benzo[b]thiophen-3-yl)-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone Drug Info
MEP --- Cathepsin B 2-tert-Butyloxycarbonylamino-6,7-methylenedioxy-1-(4-methoxyphenyl)-2H-isoquinolin-3-one Drug Info
PR --- mRNA of AR 5-Bromo-4-methoxy-2-(2,6,6-trimethyl-4-methylene-cyclohex-2-enylmethyl)-phenol Drug Info
Erbeta --- ER 3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide Drug Info
Met --- VEGFR N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide Drug Info
PR --- mRNA of AR 5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen-10-ol Drug Info
Erbeta --- ER 2-(4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[2-(4-hydroxy-phenyl)-ethylamino]-[1,3,5]triazin-2-yl}-piperazin-1-yl)-1-phenyl-ethanone Drug Info
Met --- VEGFR (S)-N-(4-(2-(4-(3-(dimethylamino)pyrrolidine-1-carbonyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide Drug Info
PR --- mRNA of AR 7,9-Difluoro-2,2,4-trimethyl-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene Drug Info
Erbeta --- ER 3,8-dihydroxy-1,7-dimethyl-6H-benzo[c]chromen-6-one Drug Info
Met --- VEGFR N1-(4-(2-(1-ethyl-1H-imidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-(2-methoxyphenyl)malonamide Drug Info
Renin --- Cathepsin D (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-4-(3-(4-methoxybut-1-ynyl)phenyl)-1-methyl-1H-imidazol-5(4H)-one Drug Info
Erbeta --- ER 5-[4-(2-dimethylamino-ethoxy)-phenyl]-5,11-dihydro-chromeno[4,3-c]chromene-2,8-diol Drug Info
MMP1 --- MMP14 (1S,2R,3R)-1-(6-Chloro-4H-thieno[3,2-b]indole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid Drug Info
Renin --- Cathepsin D (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-4-(4-fluoro-3-(3-fluoropropoxy)phenyl)-1-methyl-1H-imidazol-5(4H)-one Drug Info
Erbeta --- ER 2-Phenyl-1-thiophen-2-yl-1,2,3,4-tetrahydro-isoquinolin-6-ol Drug Info
MMP1 --- MMP3 (4-Benzyloxycarbonylamino-butyl)-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid Drug Info
S5AR --- SRD5A2 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2,6-dimethyl-phenyl)-amide Drug Info
Erbeta --- ER N-(3-hydroxy-4,7-dimethyl-6-oxo-6H-benzo[c]chromen-8-yl)methanesulfonamide Drug Info
MMP1 --- MMP3 Phosphinic acid derivative Drug Info
S5AR --- SRD5A2 ((10R,13S,17S)-17-Diisopropylcarbamoyl-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)-phosphonic acid Drug Info
Erbeta --- ER 1-(4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[2-(4-hydroxy-phenyl)-ethylamino]-[1,3,5]triazin-2-yl}-piperazin-1-yl)-3,3-dimethyl-butan-2-one Drug Info
MMP1 --- MMP9 N-[(R)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-mercapto-ethyl]-4-dimethylamino-benzamide Drug Info
S5AR --- SRD5A2 (1S,3aS,3bS,9aR,9bS,11aS)-5,9a,11a-trimethyl-1-(3-methylbutanoyl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one Drug Info
Erbeta --- ER (6-Hydroxy-2-thiophen-2-yl-benzo[b]thiophen-3-yl)-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone Drug Info
MMP1 --- MMP9 N-[(R)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-mercapto-ethyl]-isonicotinamide Drug Info
S5AR --- SRD5A2 (17-Diisopropylcarbamoyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)-acetic acid Drug Info
Erbeta --- ER 3-(4-(3-butyl-6-hydroxy-2-phenylnaphthalen-1-yloxy)phenyl)acrylic acid Drug Info
MMP13 --- MMP1 9-(4-But-2-ynyloxy-benzenesulfonyl)-6-thia-9-aza-spiro[4.5]decane-10-carboxylic acid hydroxyamide Drug Info
S5AR --- SRD5A2 4-Bromo-17-diisopropylcarbamoyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3-carboxylic acid Drug Info
Erbeta --- ER 1-Isopropyl-2-phenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol Drug Info

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