Multi-target agents
Target Pair | Drug Name | |
---|---|---|
Ftase --- FPTase | (S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propionylamino)-3-methyl-butyrylamino]-3-phenyl-propylamino}-4-methylsulfanyl-butyric acid | Drug Info |
NPKCdelta --- NPKCtheta | (E)-5-(2-(5-((2-methoxyethylamino)methyl)pyridin-2-yl)vinyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile | Drug Info |
Ftase --- FPTase | [1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-phenyl-methanol | Drug Info |
NPKCdelta --- NPKCtheta | 5-[(1E)-4-(4-Methoxypiperidin-1-yl)but-1-en-1-yl]-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile | Drug Info |
Ftase --- FPTase | 4-{5-[(S)-6-Butyl-4-(2,3-dimethyl-phenyl)-2,3-dioxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile | Drug Info |
NPKCdelta --- NPKCtheta | (E)-5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)styryl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile | Drug Info |
GSK --- VEGFR | Cyclopropanecarboxylic acid [6-(4-fluoro-phenyl)-furo[2,3-d]pyrimidin-4-yl]-amide | Drug Info |
EGFR3 --- HER2 | 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)-N-phenylpyrimidine-5-carboxamide | Drug Info |
NPKCdelta --- NPKCtheta | 5-(5-((3-hydroxypropylamino)methyl)benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile | Drug Info |
H3 --- SERT | (2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-(4-morpholinobut-1-ynyl)phenyl)-N-methylmethanamine | Drug Info |
EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[4-(benzothiazol-2-ylmethoxy)-3-chloro-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
PI3K gamma --- PI3K delta | 2-(7-methoxy-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)-6,6-dimethyl-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | Drug Info |
H3 --- SERT | (2-(4-chlorophenoxy)-5-(4-morpholinobut-1-ynyl)phenyl)-N-methylmethanamine | Drug Info |
EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyano-7-methoxyquinolin-6-yl)-4-methoxybut-2-ynamide | Drug Info |
PI3K gamma --- PI3K delta | Acetic acid (2R,3aS,5R,5bR,6S,11bR)-2-hydroxy-6-methoxymethyl-3a,5b-dimethyl-3,8,11-trioxo-2,3,3a,4,5,5b,11,11b-octahydro-1H,6H,8H-7,10-dioxa-cyclopenta[j]acephenanthrylen-5-yl ester | Drug Info |
H3 --- SERT | (6S,10bR)-9-(3-morpholinopropoxy)-6-(1H-pyrazol-5-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
EGFR3 --- HER2 | Pentanedioic acid 4-((E)-2-nitro-vinyl)-phenyl ester phenyl ester | Drug Info |
PI3K gamma --- PI3K delta | 6,6-dimethyl-2-(7-methyl-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | Drug Info |
H3 --- SERT | (5-(4-(4-isopropylpiperazin-1-yl)but-1-ynyl)-2-(4-(methylthio)phenoxy)phenyl)-N-methylmethanamine | Drug Info |
EGFR3 --- HER2 | N-(4-(3-fluorobenzyloxy)-3-(trifluoromethyl)phenyl)-6-(5-((2-(pyridin-2-ylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine | Drug Info |
PI3K gamma --- PI3K delta | 2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one | Drug Info |
HD6 --- HDAC4 | N-(cyclohexylmethyl)-2-(2,2,2-trifluoroacetyl)thiazole-5-carboxamide | Drug Info |
PPAR gamma --- PPAR delta | 3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-propionic acid | Drug Info |
EGFR3 --- HER2 | 7-(4-(Benzylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | Drug Info |
PKCA --- NPKC delta | bis(3-(trifluoromethyl)benzyl)5-(hydroxymethyl)isophthalate | Drug Info |
HDAC1 --- HD6 | 2-(5-{5-[(3-Amino-quinolinyl)-methyl]-pyridin-2-yl}-thiophen-2-yl)-2-oxoethyl Ethyl Trithiocarbonate | Drug Info |
PR --- mRNA of AR | 5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-methylene-cyclohexylmethyl)-4-methoxy-phenol | Drug Info |
EGFR3 --- HER2 | 6-(5-((benzylamino)methyl)furan-2-yl)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)thieno[2,3-d]pyrimidin-4-amine | Drug Info |
PKCA --- NPKC delta | [2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,3-dihydrofuryl]methyl 3-(4-[2-(4-Methylphenyl)ethynyl]phenoxy)propanoate | Drug Info |
HDAC1 --- HD6 | (R)-N-hydroxy-3-(3-(5-methyl-1-(1-methylpiperidin-3-yl)-4-phenyl-1H-imidazol-2-yl)phenyl)acrylamide | Drug Info |
PR --- mRNA of AR | 5-Bromo-4-methoxy-2-((1R,2S)-2-methyl-6-methylene-cyclohexylmethyl)-phenol | Drug Info |
EGFR3 --- HER2 | CHEMBL195204 | Drug Info |
PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (S)-2-benzenesulfonylamino-3-(4-hydroxy-phenyl)-propyl ester | Drug Info |
HDAC1 --- HD6 | (S)-benzyl 1-(5-phenyl-1H-1,2,4-triazol-3-yl)-5-(sulfamoylamino)pentylcarbamate | Drug Info |
PR --- mRNA of AR | rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-phenylpropan-1-one | Drug Info |
EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyanoquinolin-6-yl)-4-methoxybut-2-ynamide | Drug Info |
PPAR gamma --- 5LOX | 2-(4-chloro-6-(isopentylamino)pyrimidin-2-ylthio)-2-(naphthalen-1-yl)acetic acid | Drug Info |
HDAC1 --- HD6 | (S)-ethyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(sulfamoylamino)hexan-2-ylcarbamate | Drug Info |
PR --- mRNA of AR | (R)-3-(4-Hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(thiazol-2-yl)-propanamide | Drug Info |
EGFR3 --- HER2 | 6,7-dimethoxy-4-(3-(trifluoromethyl)phenylamino)quinoline-3-carbonitrile | Drug Info |
PPAR gamma --- PPAR delta | 2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenoxy}-propionic acid | Drug Info |
HDAC1 --- HD6 | Ethyl 2-(4-Methoxyphenyl)-2-oxoethyl Trithiocarbonate | Drug Info |
PR --- mRNA of AR | 8-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one | Drug Info |
EGFR3 --- HER2 | 2-(2-(3,5-Dibromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
PPAR gamma --- PPAR delta | 2-(S)-2-(2-benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid | Drug Info |
HDAC1 --- HDAC2 | N-hydroxy-7-(5-phenyloxazol-2-yl)heptanamide | Drug Info |
PR --- mRNA of AR | N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfonamide | Drug Info |
ER --- mRNA of AR | 3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-2-one | Drug Info |
PPAR gamma --- PPAR delta | 2-(5-chloro-2-methyl-4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)phenoxy)acetic acid | Drug Info |
HDAC1 --- HDAC2 | N-hydroxy-7-(4-phenylthiazol-2-yl)heptanamide | Drug Info |
Pagination
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