Multi-target agents
Target Pair | Drug Name | |
---|---|---|
MMP13 --- MMP1 | 4-{(R)-Carboxy-[5-(4'-ethoxyphenyl)-thiophene-2-sulfonylamino]-methyl}-piperidine-1-carboxylic Acid 4-Tetrahydropyranyl Ester | Drug Info |
S5AR --- SRD5A2 | (4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-10-propyl-hexadecahydro-indeno[5,4-f]quinolin-2-one | Drug Info |
Erbeta --- ER | 4-{6-Hydroxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-benzamide | Drug Info |
MMP13 --- MMP1 | (2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-benzenesulfonyl]-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide | Drug Info |
S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-N-trityl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
Erbeta --- ER | 5'-(2-hexahydro-1-pyridinylethoxy)-5-hydroxy-2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-1',3'-dione | Drug Info |
MMP13 --- MMP1 | (R)-[5-(4'-Methoxyphenyl)-thiophene-2-sulfonylamino]-(1-tertbutylcarbamoyl-piperidin-4-yl)-acetic Acid | Drug Info |
S5AR --- SRD5A2 | 4-Cyano-17-diisopropylcarbamoyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3-carboxylic acid | Drug Info |
Erbeta --- ER | 5-(5-Hydroxy-2-naphthyl)biphenyl-2-ol | Drug Info |
MMP13 --- MMP1 | 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2-carbonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide | Drug Info |
S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-5-benzyl-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
Erbeta --- ER | 4-bromo-7-hydroxy-9a-phenyl-1,2,9,9a-tetrahydrofluoren-3-one | Drug Info |
MMP13 --- MMP1 | (R)-[5-(4'-Methoxyphenyl)-thiophene-2-sulfonylamino]-(1-diethylcarbamoylpiperidin-4-yl)-acetic Acid | Drug Info |
ABL --- Src | 4-(2,4-Dichloro-5-methoxy-phenylamino)-6-methoxy-7-[3-(3,4,5-trimethyl-piperazin-1-yl)-propoxy]-quinoline-3-carbonitrile | Drug Info |
Erbeta --- ER | 4-(2-{4-[3-(4-Chloro-phenyl)-propylsulfanyl]-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino}-ethyl)-phenol | Drug Info |
MMP13 --- MMP14 | 5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrrol-1-yl-phenoxy)-phenoxy]-piperidine-2,4,6-trione | Drug Info |
ABL --- Src | (2,4-Dichloro-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-amine | Drug Info |
Erbeta --- ER | 2-(6-hydroxynaphthalen-2-yl)benzo[d]oxazol-5-ol | Drug Info |
MMP13 --- MMP14 | CHEMBL1784354 | Drug Info |
FGFR --- Src | 1-[6-(2,6-Dichloro-phenyl)-2-(2-diethylamino-ethylamino)-pyrido[2,3-d]pyrimidin-7-yl]-3-ethyl-urea | Drug Info |
Erbeta --- ER | 2-(3-Fluoro-4-hydroxy-phenyl)-7-methyl-benzofuran-5-ol | Drug Info |
MMP13 --- MMP9 | 2-[Benzyl-(4-benzyloxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide | Drug Info |
TRIP5 --- mRNA of KIF11 | N-(3-aminopropyl)-N-(1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)propyl)-4-(trifluoromethoxy)benzamide | Drug Info |
Erbeta --- ER | [6-Chloro-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone; hydrochloride | Drug Info |
MMP2 --- MMP1 | N-Hydroxy-N-[1-(4'-methyl-biphenyl-4-yloxymethyl)-2-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-yl)-ethyl]-formamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 2-(trifluoromethoxy)-9H-carbazole | Drug Info |
Erbeta --- Mcl1 | SID56373548 | Drug Info |
MMP2 --- MMP13 | (S)-N-(cyclohexylmethyl)-4-(4-((3-hydroxyquinuclidin-3-yl)ethynyl)phenoxy)benzamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 10-(Trifluoromethyl)-2,3,5,12-tetrahydroazepino[3,2-a]carbazol-4(1H)-one | Drug Info |
Ftase --- FPTase | 2-(2,4-Dichloro-benzenesulfinyl)-4-imidazol-1-ylmethyl-benzonitrile | Drug Info |
MMP2 --- MMP13 | (S)-3-methyl-2-(4-(5-(4-(methylsulfonamido)benzofuran-2-carboxamido)pyridin-2-yl)phenylsulfonamido)butanoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | 3-(2,5-difluorophenyl)-N-methyl-5-phenyl-4,5-dihydropyrazole-1-carboxamide | Drug Info |
Ftase --- FPTase | 4-((R)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid pyridin-3-ylamide | Drug Info |
MMP2 --- MMP13 | (S)-3-methyl-2-(4'-(3-methyl-4-phenylbenzofuran-2-carboxamido)biphenyl-4-ylsulfonamido)butanoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | 4'-(trifluoromethyl)-4-biphenylyl carbamate | Drug Info |
Ftase --- FPTase | ethyl 2-(3-(3-(1H-imidazol-4-yl)propyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)acetate | Drug Info |
MMP2 --- MMP13 | (R)-N-hydroxy-3-methyl-2-(N-(pyridin-3-ylmethyl)naphthalene-2-sulfonamido)butanamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 1-[(3R,3aR)-8-fluoro-3-(3-morpholin-4-yl-propyl)-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl]-ethanone | Drug Info |
Ftase --- FPTase | 3-(3-(1H-imidazol-1-yl)propyl)-1-(3-chlorobenzyl)-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione | Drug Info |
MMP2 --- MMP13 | (R)-N-hydroxy-3-methyl-2-(N-(pyridin-2-ylmethyl)naphthalene-2-sulfonamido)butanamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 2-(3'-Hydroxyphenyl)-3-benzyl-6-(piperidin-1-yl)-1,4-dihydroquinoline-4-one | Drug Info |
Ftase --- FPTase | 4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-2-(5,6,7,8-tetrahydro-naphthalen-2-yloxy)-benzonitrile | Drug Info |
MMP2 --- MMP13 | 5-Phenyl-2-(4-phenylazo-benzenesulfonylamino)-pent-4-ynoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | (R)-2-amino-3-((4-isopropylphenyl)diphenylmethylthio)propanoic acid | Drug Info |
Ftase --- FPTase | N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)-N-(4-phenoxyphenyl)quinoline-2-carboxamide | Drug Info |
MMP2 --- MMP14 | cis-(2R,3R)-2-(3,5-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate | Drug Info |
TRIP5 --- mRNA of KIF11 | N-{4'-[(trifluoromethyl)sulfonyl]-4-biphenyl}urea | Drug Info |
Ftase --- FPTase | 1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-3-yl-ethanone | Drug Info |
MMP2 --- MMP3 | N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-acetamide | Drug Info |
TRIP5 --- mRNA of KIF11 | 4-Amino-1-[3-(2-chloro-phenyl)-5-(3-hydroxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-butan-1-one | Drug Info |
Pagination
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