Multi-target agents
Target Pair | Drug Name | |
---|---|---|
H3 --- SERT | N-(4-(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)phenyl)but-3-ynyl)-N-methylcyclopropanamine | Drug Info |
EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-2-dimethylaminomethyl-acrylamide | Drug Info |
PI3K gamma --- PI3K delta | CHEMBL1645108 | Drug Info |
VEGFR2 --- VEGFR1 | N-(3,4-dimethoxyphenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazole-5-carboxamide | Drug Info |
H3 --- SERT | 4-(3,4-dichlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-quinazolin-6-yl]-acrylamide | Drug Info |
PI3K gamma --- PI3K delta | (R)-2-(3-benzylmorpholino)-5,5-dimethyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one | Drug Info |
VEGFR2 --- VEGFR1 | N-(3,4-dichlorophenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide | Drug Info |
H3 --- SERT | 4-(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzonitrile | Drug Info |
EGFR3 --- HER2 | 4-(3-bromophenylamino)-6,7-dihydroxyquinoline-3-carbonitrile | Drug Info |
PI3K gamma --- PI3K delta | 6,6-dimethyl-2-(6-phenyl-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | Drug Info |
VEGFR2 --- VEGFR1 | N-(4-isopropylphenyl)-4-(2-(isoxazol-4-yl)ethyl)thiazole-5-carboxamide | Drug Info |
H3 --- SERT | N-ethyl-3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)propan-1-amine | Drug Info |
EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)-2-fluoro-N-(2-(pyrrolidin-1-yl)ethyl)acrylamide | Drug Info |
PKCA --- NPKC delta | 2-{2,6-Dihydroxy-4-[(3R,4R)-2-(4-hydroxy-benzoylamino)-cyclopentyloxymethyl]-benzoyl}-3-hydroxy-benzoic acid | Drug Info |
VEGFR2 --- VEGFR1 | 2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(pyridin-4-ylmethyl)aniline | Drug Info |
HDAC1 --- HD6 | (S)-benzyl 1-(2-(4-methoxyphenyl)thiazol-4-yl)-5-(sulfamoylamino)pentylcarbamate | Drug Info |
EGFR3 --- HER2 | N-(4-(o-tolylamino)quinazolin-6-yl)acrylamide | Drug Info |
PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3R,4R)-3-(4-hydroxy-benzoylamino)-1-(toluene-4-sulfonyl)-azepan-4-yl ester | Drug Info |
VEGFR2 --- VEGFR1 | 1-[3-(4-Methyl-piperazin-1-yl)-propyl]-4-(3-thiophen-3-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-1H-pyridin-2-one | Drug Info |
HDAC1 --- HD6 | N-hydroxy-3-(3-(1-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(6-fluoroquinolin-4-yloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-methanesulfonyl-cyclopentyl ester | Drug Info |
VEGFR2 --- VEGFR1 | 1-(3-Piperidin-1-yl-propyl)-3-(5-thiophen-3-yl-pyridin-3-yl)-1H-indole | Drug Info |
HDAC1 --- HD6 | N1-hydroxy-N8-(4-((2R,4S,6R)-4-phenyl-6-((pyridin-4-ylthio)methyl)-1,3-dioxan-2-yl)phenyl)octanediamide | Drug Info |
EGFR3 --- HER2 | CHEMBL258282 | Drug Info |
PKCA --- NPKCtheta | 3-(5-(4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione | Drug Info |
VEGFR2 --- VEGFR1 | 3-Chloro-N-(2,4-dichloro-benzoyl)-4-fluoro-benzenesulfonamide | Drug Info |
HDAC1 --- HD6 | N-hydroxy-3-(3-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
EGFR3 --- HER2 | SID85267487 | Drug Info |
PPAR gamma --- LXRalpha | 2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid | Drug Info |
HDAC1 --- HD6 | Ethyl 2-oxo-2-(4-{[(1-phenyl-methanoyl)-amino]-methyl}-phenyl)-ethyl trithiocarbonate | Drug Info |
EGFR3 --- HER2 | N4-(3-bromophenyl)-N6-methylquinazoline-4,6-diamine | Drug Info |
PPAR gamma --- PPAR delta | 5-methyl-2-(3-(6-methyl-1H-indol-1-ylsulfonyl)benzamido)benzoic acid | Drug Info |
HDAC1 --- HD6 | N-hydroxy-3-(3-(1-methyl-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
EGFR3 --- MCSF | (6,7-Dimethyl-quinazolin-4-yl)-methyl-m-tolyl-amine; hydrochloride | Drug Info |
PPAR gamma --- PPAR delta | (R)-3-{(S)-4-[(E)-5-(4-{5-[4-(2-Carboxy-2-ethoxy-ethyl)-phenoxy]-3-methyl-pent-3-en-1-ynyl}-phenyl)-3-methyl-pent-2-en-4-ynyloxy]-phenyl}-2-ethoxy-propionic acid | Drug Info |
HDAC1 --- HDAC2 | N-hydroxy-7-(5-(4-methoxyphenyl)oxazol-2-yl)heptanamide | Drug Info |
Erbeta --- ER | 4-[1-(1-Methyl-butyl)-1,7a-dihydro-pyrrolo[2,1,5-cd]indolizin-2-yl]-phenol | Drug Info |
PPAR gamma --- PPAR delta | 3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid | Drug Info |
HDAC1 --- HDAC2 | 6-Methoxy-1H-indole-2-carboxylic acid (6-hydroxycarbamoyl-hexyl)-amide | Drug Info |
Erbeta --- ER | 4-[4-(2-hexahydro-1-pyridinylethoxy)phenyl]-3-phenyl-(3S,4R)-3,4-dihydro-2H-7-chromenol | Drug Info |
PPAR gamma --- PPAR delta | (S)-3-{4-[3,3-Bis-(4-furan-2-yl-phenyl)-allyloxy]-phenyl}-2-ethoxy-propionic acid | Drug Info |
HDAC1 --- HDAC2 | 4-(3-(3,4-Dimethoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
Erbeta --- ER | (2S,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-chroman-4-one | Drug Info |
PPAR gamma --- PPAR delta | 4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-propoxy]-phenyl}-butyric acid | Drug Info |
HDAC1 --- HDAC2 | Thailandepsin B | Drug Info |
Erbeta --- ER | 4-hydroxy-N-(4-hydroxyphenyl)-N-(3,3,3-trifluoropropyl)benzenesulfonamide | Drug Info |
PPAR gamma --- PPAR delta | 3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-propionic acid | Drug Info |
HDAC1 --- HDAC4 | (R)-N2-hydroxy-N5-(1-phenylethyl)thiophene-2,5-dicarboxamide | Drug Info |
Pagination
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