Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- VEGFR1 | 2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N-(pyridin-4-ylmethyl)aniline | Drug Info |
| HDAC1 --- HDAC2 | 1H-Indole-7-carboxylic acid (5-hydroxycarbamoyl-pentyl)-amide | Drug Info |
| ER --- PR | 17alpha-Ethynyl-17-hydroxy-18-ethyl-4-estren-3-one | Drug Info |
| PPAR gamma --- PPAR delta | (R)-3-(1-((5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)-1H-indol-5-yl)-2-propoxypropanoic acid | Drug Info |
| VEGFR2 --- VEGFR1 | N-(4-(chlorodifluoromethoxy)phenyl)-1-(2-(pyridin-4-yl)ethyl)-1H-pyrazole-5-carboxamide | Drug Info |
| HDAC1 --- HDAC2 | 2-oxo-nonanedioic acid 9-biphenyl-3-ylamide 1-methylamide | Drug Info |
| Erbeta --- ER | 6-(3,4-difluorophenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)naphthalen-2-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-(2-(benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)ethyl)phenoxy)propanoic acid | Drug Info |
| VEGFR2 --- VEGFR1 | (5-Ethanesulfonyl-2-methoxy-phenyl)-[5-(4-methoxy-phenyl)-oxazol-2-yl]-amine | Drug Info |
| HDAC1 --- HDAC2 | 4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide | Drug Info |
| Erbeta --- ER | methyl 2,3-bis(4-hydroxyphenyl)propanoate | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butoxy)phenoxy)-2-methylpropanoic acid | Drug Info |
| VEGFR2 --- VEGFR1 | N-(3-chloro-4-(trifluoromethyl)phenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazole-5-carboxamide | Drug Info |
| HDAC1 --- HDAC2 | 3-[4-(Biphenyl-4-yloxy)-butylsulfanyl]-1,1,1-trifluoro-propan-2-one | Drug Info |
| Erbeta --- ER | 4-[5-Hydroxy-2-(4-hydroxy-phenyl)-3H-inden-1-yl]-benzamide | Drug Info |
| PPAR gamma --- PPAR delta | (S)-5-(3-(3-(4-cycloheptyl-2-propylphenoxy)propoxy)phenyl)oxazolidine-2,4-dione | Drug Info |
| VEGFR2 --- VEGFR1 | GW580509X | Drug Info |
| HDAC1 --- HDAC4 | (S)-benzyl 1-(cyclopentylamino)-7-mercapto-1-oxoheptan-2-ylcarbamate | Drug Info |
| Erbeta --- ER | 1-[4-(4-Cyclopentyl-piperazin-1-yl)-phenyl]-2-(3-hydroxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-((2-fluoro-4-(trifluoromethyl)benzyl)carbamoyl)-4-methoxybenzyl)butanoic acid | Drug Info |
| VEGFR2 --- VEGFR1 | 2-((1H-pyrrolo[3,2-c]pyridin-1-yl)methyl)-N-(4-chloro-3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| HDAC2 --- HDAC4 | N-hydroxy-2,3-diphenylpropanamide | Drug Info |
| Erbeta --- ER | 9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one | Drug Info |
| PPAR gamma --- PPAR delta | (S)-3-[4-(3-biphenyl-4-yl-but-2enyloxy)-phenyl]-2-ethoxy-propionic acid | Drug Info |
| VEGFR2 --- VEGFR1 | 1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)phenyl)-1H-imidazole-2-carboxamide | Drug Info |
| HER2 --- MMP-2 | (6S,7S)-N-hydroxy-6-(3,4,10,10a-tetrahydropyrazino[1,2-a]indol-2(1H)-ylcarbonyl)-5-azaspiro[2.5]octane-7-carboxamide | Drug Info |
| Erbeta --- ER | 7,9-dibromo-3-hydroxy-4-methyl-6H-benzo[c]chromen-6-one | Drug Info |
| PPAR gamma --- PPAR delta | (S)-3-(4-(2-(2-cyclohexyl-5-methyloxazol-4-yl)ethoxy)phenyl)-2-methyl-2-phenoxypropanoic acid | Drug Info |
| JAK2 --- STK1 | 5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole | Drug Info |
| Erbeta --- ER | 4-{Cyclohexylidene-[4-(2-diisopropylamino-ethoxy)-phenyl]-methyl}-phenol | Drug Info |
| PPAR gamma --- PPAR delta | 4-Isocyanato-benzoic acid 2-((2,4-bis-trifluoromethyl-benzyl)-{3-[3-(1-carboxy-1-methyl-ethoxy)-phenyl]-propyl}-amino)-ethyl ester | Drug Info |
| JNK1 --- JNK3 | N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)nicotinamide | Drug Info |
| Erbeta --- ER | CHEMBL1192929 | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)propyl)amino)methyl)phenoxy)butanoic acid | Drug Info |
| JNK1 --- JNK3 | N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(7-cyano-2-oxoquinolin-1(2H)-yl)acetamide | Drug Info |
| Erbeta --- ER | (6-Hydroxy-2-p-tolyl-benzo[b]thiophen-3-yl)-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone; hydrochloride | Drug Info |
| PPAR gamma --- PPAR delta | (R)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)benzyl)butanoic acid | Drug Info |
| JNK1 --- JNK3 | N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-isobutoxypicolinamide | Drug Info |
| Erbeta --- ER | 4-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fluoren-4-yl)phenoxy]ethyl}morpholine | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-((3-(3-fluoro-4-(trifluoromethoxy)phenyl)-1,2,4-thiadiazol-5-yl)methylsulfanyl)-2-methylphenoxy)-2-methylpropanoic acid | Drug Info |
| JNK1 --- JNK3 | N-(4-(methylsulfonyl)benzyl)-4-amino-6-ethoxy-5-(3-hydroxyprop-1-ynyl)picolinamide | Drug Info |
| Erbeta --- ER | (2R,3S)-5-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | (S)-5-(3-(3-(4-(cyclopentyloxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione | Drug Info |
| JNK1 --- JNK3 | 3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(piperidin-4-yl)benzamide | Drug Info |
| Erbeta --- ER | 3-Chloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin-1-yl-ethoxy)-phenyl]-4,5-dihydro-1H-imidazol-4-yl}-phenol | Drug Info |
| JNK1 --- JNK3 | methyl 4-methyl-2-(2-(4-(3-(piperidin-1-yl)propoxy)phenyl)acetamido)thiophene-3-carboxylate | Drug Info |
| Erbeta --- ER | (S)-9a-ethyl-1-fluoro-6-(trifluoromethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one | Drug Info |
| JNK1 --- JNK3 | 5-bromo-N-(3-chloro-2-(4-(furan-2-ylmethyl)piperazin-1-yl)phenyl)furan-2-carboxamide | Drug Info |
| Erbeta --- ER | 4-(2-{4-[Methyl-(3-p-tolyl-propyl)-amino]-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino}-ethyl)-phenol | Drug Info |
| JNK1 --- JNK3 | SID17506592 | Drug Info |
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