Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| S5AR --- SRD5A2 | 7-((E)-Styryl)-9,10-dihydro-phenanthrene-2-carboxylic acid | Drug Info |
| Erbeta --- ER | 4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[4-(2-methyl-thiazol-4-ylmethyl)-piperazin-1-yl]-[1,3,5]triazin-2-ylamino}-ethyl)-phenol | Drug Info |
| MMP1 --- MMP9 | Furan-3-carboxylic acid [(R)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-mercapto-ethyl]-amide | Drug Info |
| S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-N-(4'-tert-butyl-4-(trifluoromethyl)biphenyl-2-yl)-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
| Erbeta --- ER | [2-(4-{Cyclohexylidene-[4-(2-diisopropylamino-ethoxy)-phenyl]-methyl}-phenoxy)-ethyl]-diisopropyl-amine | Drug Info |
| MMP13 --- MMP1 | 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-isobutyryl-1,4-diazepane-5-carboxamide | Drug Info |
| S5AR --- SRD5A2 | 6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid | Drug Info |
| Erbeta --- ER | 4-(2-{4-[3-(4-Chloro-phenyl)-propylamino]-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino}-ethyl)-phenol | Drug Info |
| MMP13 --- MMP1 | 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-piperazin-1-ylmethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-N,N-dibenzyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide | Drug Info |
| Erbeta --- ER | 7-(3-Fluoro-4-hydroxy-phenyl)-3-hydroxy-naphthalene-1-carbaldehyde | Drug Info |
| MMP13 --- MMP1 | 4-benzylbenzyl(2-(cyclopropylmethyl)-3-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-ylamino)-3-oxopropyl)phosphinic acid | Drug Info |
| S5AR --- SRD5A2 | ((S)-7-Chloro-4a-methyl-3,4,4a,9-tetrahydro-phenanthren-2-yl)-phosphinic acid | Drug Info |
| Erbeta --- ER | 4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol | Drug Info |
| MMP13 --- MMP1 | 4-(4-Methoxy-phenyl)-5-oxo-pyrrolidine-2-carboxylic acid hydroxyamide | Drug Info |
| ABL --- Src | 4-(2,4-Dichloro-phenylsulfanyl)-6,7-dimethoxy-quinoline-3-carbonitrile | Drug Info |
| Erbeta --- ER | (2R,3R,4S)-3-(4-Hydroxy-phenyl)-4-methyl-2-{4-[2-((S)-3-methyl-pyrrolidin-1-yl)-ethoxy]-phenyl}-chroman-6-ol | Drug Info |
| MMP13 --- MMP14 | 5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrazol-1-yl-phenoxy)-phenoxy]-piperidine-2,4,6-trione | Drug Info |
| ABL --- Src | 4-(2,4-Dichloro-5-methoxy-phenylamino)-6-methoxy-7-[3-(2-morpholin-4-yl-ethylamino)-propoxy]-quinoline-3-carbonitrile | Drug Info |
| Erbeta --- ER | [4-Bromo-5-hydroxy-2-(4-hydroxy-phenyl)-benzofuran-7-yl]-acetonitrile | Drug Info |
| MMP13 --- MMP14 | 5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-[1,2,4]triazol-4-yl-phenoxy)-phenoxy]-piperidine-2,4,6-trione | Drug Info |
| FGFR --- Src | 1-[7-Amino-3-(2,6-dichloro-phenyl)-[1,6]naphthyridin-2-yl]-3-ethyl-urea | Drug Info |
| Erbeta --- ER | (2S,3R)-3-(4-hydroxyphenyl)-2-(4-((R)-3-methyl-2-(pyrrolidin-1-yl)butoxy)phenyl)-2,3-dihydrobenzo[b][1,4]oxathiin-6-ol | Drug Info |
| MMP13 --- MMP9 | N-hydroxy-2-(4-methoxyphenylsulfonyl)tetradecanamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(3-(dimethylamino)propyl)-N,7,8-trimethyl-4-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxamide | Drug Info |
| Erbeta --- ER | 2-Chloro-2,2-difluoro-1-(6-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone | Drug Info |
| MMP2 --- MMP1 | 4-Methyl-2-((R)-2-oxo-2-pyridin-2-yl-ethyl)-pentanoic acid [2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-amide | Drug Info |
| TRIP5 --- mRNA of KIF11 | SID24790162 | Drug Info |
| Erbeta --- Mcl1 | SID14746067 | Drug Info |
| MMP2 --- MMP13 | (R)-N-hydroxy-3-(4-hydroxyphenyl)-2-(N-isopentylnaphthalene-2-sulfonamido)propanamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(3-aminopropyl)-N-(1-(3-benzyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)propyl)-2,4-dichlorobenzamide | Drug Info |
| Ftase --- FPTase | 3-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid methyl ester | Drug Info |
| MMP2 --- MMP13 | 2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-morpholin-4-yl-hex-4-ynoic acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | 1-[3-(2-Chloro-phenyl)-5-(3-hydroxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-2-methyl-propan-1-one | Drug Info |
| Ftase --- FPTase | 4-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid methyl ester | Drug Info |
| MMP2 --- MMP13 | 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dichloroisonicotinoyl)-N-hydroxypiperidine-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 1-(3-(2-chlorophenyl)-5-(3-hydroxyphenyl)-4,5-dihydropyrazol-1-yl)ethanone | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-piperidine-1-carboxamidine | Drug Info |
| MMP2 --- MMP13 | 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(1,2-dimethyl-1H-imidazol-4-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 1-{(3R,3aR)-3-[3-(4-acetyl-piperazin-1-yl)-propyl]-8-chloro-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl}-ethanone | Drug Info |
| Ftase --- FPTase | (S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-naphthalene-1-carbonyl]-amino}-hexanoic acid | Drug Info |
| MMP2 --- MMP13 | 4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 4,5-Dibromo-1H-pyrrole-2-carboxylic acid(4-fluorobenzyloxy)-amide | Drug Info |
| Ftase --- FPTase | N-Isopropyl-2-[2-(2-methoxy-phenyl)-1H-indol-3-yl]-N-pyridin-4-ylmethyl-acetamide | Drug Info |
| MMP2 --- MMP13 | (R)-N-hydroxy-3-methyl-2-(N-(pyridin-4-ylmethyl)naphthalene-2-sulfonamido)butanamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | 3-amino-N-methyl-N-(((2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)methyl)propane-1-sulfonamide | Drug Info |
| Ftase --- FPTase | Lithium; (S)-2-({5-[5-(4-fluoro-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate | Drug Info |
| MMP2 --- MMP14 | (S)-2-{4'-[(Benzofuran-2-ylmethyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid | Drug Info |
| TRIP5 --- mRNA of KIF11 | 1-[4-[3-(4-acetyl-piperazin-1-yl)-propyl]-1-(2-fluoro-5-methyl-phenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-ethanone | Drug Info |
| Ftase --- FPTase | 1-[3-Benzyl-7-bromo-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-ethanone | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.