Multi-target agents
Target Pair | Drug Name | |
---|---|---|
Erbeta --- ER | SID87341147 | Drug Info |
MEP --- Cathepsin B | (S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)biphenyl-4-yl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanamide | Drug Info |
PR --- mRNA of AR | rac-3-(4-Nitrophenylamino)-1,3-bis(3-fluorophenyl)propan-1-one | Drug Info |
Erbeta --- ER | SID137275923 | Drug Info |
Met --- VEGFR | N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamoyl)-2-phenylacetamide | Drug Info |
PR --- mRNA of AR | CHEMBL414318 | Drug Info |
Erbeta --- ER | 4-[6-(Isobutyl-methyl-amino)-4-phenyl-pyridin-2-yl]-2-methyl-phenol | Drug Info |
Met --- VEGFR | 3-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenylamino)-4,4,4-trifluoro-N-phenylbutanamide | Drug Info |
PR --- mRNA of AR | 5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-2,3-dihydroquinolin-4(1H)-one O-isopropyl oxime | Drug Info |
Erbeta --- ER | (R)-5-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-phenyl}-11,12-dihydro-5H-6,13-dioxa-benzo[3,4]cyclohepta[1,2-a]naphthalene-2,8-diol | Drug Info |
Met --- VEGFR | N1-(4-(2-(1-ethyl-1H-imidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-(2-hydroxyphenyl)malonamide | Drug Info |
Renin --- Cathepsin D | 2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexylmethyl-N*1*-(1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-N*4*-{[methyl-(2-pyridin-2-yl-ethyl)-carbamoyl]-methyl}-succinamide (BILA 2157 BS) | Drug Info |
Erbeta --- ER | (R)-6-bromo-9a-(cyclopropylmethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one | Drug Info |
MMP1 --- MMP3 | (2R)-N-hydroxy-4-methyl-2-{[methyl(phenyl)phosphoryl]amino}pentanamide | Drug Info |
S5AR --- SRD5A2 | (1S,3aS,3bS,7aR,8aS,8bS,8cS,10aS)-N,N-diethyl-5,8b,10a-trimethyl-7-oxo-1,2,3,3a,3b,4,5,7,7a,8,8a,8b,8c,9,10,10a-hexadecahydrocyclopenta[i]cyclopropa[a]phenanthridine-1-carboxamide | Drug Info |
Erbeta --- ER | [6-Hydroxy-2-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone | Drug Info |
MMP1 --- MMP3 | (R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-phenyl-propylamino]-6-phenyl-hexanoic acid | Drug Info |
S5AR --- SRD5A2 | (1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylic acid tert-butylamide | Drug Info |
Erbeta --- ER | 2-(4-Hydroxy-phenyl)-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophene-6-carboxylic acid methyl ester; hydrochloride | Drug Info |
MMP1 --- MMP3 | (R)-2-[4-(4-Chloro-phenoxy)-butyl]-N*1*-{(S)-2,2-dimethyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-propyl}-N*4*-hydroxy-succinamide | Drug Info |
S5AR --- SRD5A2 | 17-Diisopropylcarbamoyl-13-methyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid | Drug Info |
Erbeta --- ER | 2-(3-fluoro-4-hydroxyphenyl)-7-(2-fluorovinyl)benzo[d]oxazol-5-ol | Drug Info |
MMP1 --- MMP9 | (2S,11S,12R)-12-Isobutyl-13-oxo-1,7diaza-cyclotridecane-2,11-dicarboxylic acid 11-hydroxyamide 2-methylamide; hydrochloride | Drug Info |
S5AR --- SRD5A2 | 5-Bromo-pentanoic acid pentyl-((4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-amide | Drug Info |
Erbeta --- ER | 10-[4-(2-Azepan-1-yl-ethoxy)-benzyl]-10H-benzo[4,5]thieno[3,2-b]indol-7-ol | Drug Info |
MMP13 --- MMP1 | (R)-3-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-tetrahydro-furan-3-carboxylic acid hydroxyamide | Drug Info |
S5AR --- SRD5A2 | (1S,9aR,11aS)-1-(2,6-Difluoro-benzoyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridin-7-one | Drug Info |
Erbeta --- ER | 1-Hydroxy-3,6-dimethoxy-9H-xanthen-9-one | Drug Info |
MMP13 --- MMP1 | (2R,3S)-4-Methanesulfonyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide | Drug Info |
S5AR --- SRD5A2 | (4aR,6aS)-7-(Indole-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one | Drug Info |
Erbeta --- ER | 2-Benzo[1,3]dioxol-5-ylmethyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
MMP13 --- MMP1 | 4-{(R)-Carboxy-[5-phenylthiophene-2-sulfonylamino]-methyl}piperidine-1-carboxylic Acid iso-propyl Ester | Drug Info |
S5AR --- SRD5A2 | (1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-1-(3-methylbutanoyl)-3,3a,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[i]phenanthridin-7(2H)-one | Drug Info |
Erbeta --- ER | 4-{(Z)-1-[4-(2-Dimethylamino-ethoxy)-phenyl]-hept-1-enyl}-phenol | Drug Info |
MMP13 --- MMP1 | (S)-N-hydroxy-2,2-dimethyl-4-(4-(prop-2-ynyloxy)phenylsulfonyl)thiomorpholine-3-carboxamide | Drug Info |
S5AR --- SRD5A2 | 9,10-Dihydro-phenanthrene-2-carboxylic acid | Drug Info |
Erbeta --- ER | 5-Chloro-2-(4-hydroxy-phenyl)-quinolin-6-ol | Drug Info |
MMP13 --- MMP1 | (2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1-carboxylic acid ethyl ester | Drug Info |
ABL --- Src | 4-(2,4-Dichloro-5-methoxy-phenylamino)-6-methoxy-7-(3-piperidin-1-yl-propoxy)-quinoline-3-carbonitrile | Drug Info |
Erbeta --- ER | (R)-2-(1-(4-(2-(piperidin-1-yl)ethoxy)benzyl)-2-phenyl-1H-indol-3-yl)-N-(4-(4-hydroxyphenyl)butan-2-yl)acetamide | Drug Info |
MMP13 --- MMP14 | 4-{4-[5-Amino-3-(2-ethoxy-ethyl)-2,4,6-trioxo-piperidin-3-yloxy]-phenoxy}-benzonitrile | Drug Info |
ABL --- Src | 4-(2,4-Dichloro-5-methoxy-phenylamino)-6-methoxy-7-(3-piperazin-1-yl-propoxy)-quinoline-3-carbonitrile | Drug Info |
Erbeta --- ER | 5S-(-)-[4-(2-diethylaminoethoxy)phenyl]-11,12-dihydro-5H-6,13-dioxabenzo-[3,4]cyclohepta[1,2-a]naphthalen-2-ol | Drug Info |
MMP13 --- MMP8 | 3-(4-Phenylsulfanyl-benzenesulfonyl)-cyclohexanethiol | Drug Info |
FGFR --- Src | N-{6-(2,6-Dichloro-phenyl)-2-[3-(4-methyl-piperazin-1-yl)-propylamino]-pyrido[2,3-d]pyrimidin-7-yl}-2-phenyl-acetamide | Drug Info |
Erbeta --- ER | 5-phenyl-5,11-dihydro-chromeno[4,3-c]chromene-2,8-diol | Drug Info |
MMP2 --- HER2 | (5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenyl-2,5-dihydro-1H-pyrrole-1-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate | Drug Info |
TRIP5 --- mRNA of KIF11 | 1-((S)-5-(3-((1R,4R)-5-oxa-2-aza-bicyclo[2.2.1]heptan-2-yl)propyl)-3-(2,5-difluorophenyl)-5-phenyl-4,5-dihydropyrazol-1-yl)ethanone | Drug Info |
Erbeta --- ER | 4-(6-Hydroxy-benzo[b]thiophen-2-yl)-benzene-1,2-diol | Drug Info |
MMP2 --- MMP1 | (S)-2,2-Dimethyl-4-[4-(pyridin-3-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide | Drug Info |
Pagination
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