Target Pair Drug Name
Ftase --- FPTase 1-[(2R,3R)-3-(2-Chloro-6-fluoro-benzyloxy)-5-fluoro-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
MMP2 --- MMP9 2-(7-Benzyloxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide Drug Info
VEGFR2 --- Ckit (3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione Drug Info
Ftase --- FPTase 1-(3-Chloro-phenyl)-4-[3-(2-methoxy-4'-trifluoromethyl-biphenyl-4-ylmethyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one Drug Info
MMP2 --- MMP9 (R)-4-Amino-2-[(biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-butyramide Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino)methyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide Drug Info
Ftase --- FPTase 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-pyridin-3-yl-piperidine-1-carboxamidine Drug Info
MMP3 --- MMP8 4-Methoxy-benzenesulfonic acid 3-hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl ester Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Drug Info
Ftase --- FPTase 6-[(2'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile Drug Info
MMP3 --- MMP8 2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide Drug Info
VEGFR2 --- Cmet rac-N-(3-Fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl)-1-(2-hydroxypropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide Drug Info
Ftase --- FPTase 6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-5-(2,2-difluoro-benzo[1,3]dioxol-5-yl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile Drug Info
MMP9 --- MMP3 2-(1-Hydroxy-2-mercapto-ethyl)-nonanoic acid [(S)-3-methyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-butyl]-amide Drug Info
VEGFR2 --- CSrc 4-{1-[(Benzyloxy)methyl]-1H-indol-3-yl}-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one Drug Info
Ftase --- FPTase (S)-2-({5-[2-((E)-4-Methoxy-pyridin-3-yl)-vinyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid Drug Info
mTOR --- AKT N-(6-(6-Chloro-5-(3-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide Drug Info
VEGFR2 --- CSrc N-(4-methyl-3-(1-(6-(2-(pyrrolidin-2-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide Drug Info
Ftase --- FPTase (S)-2-[(5-{2-[(E)-4-(Hydroxy-phenyl-methyl)-pyridin-3-yl]-vinyl}-2'-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid Drug Info
mTOR --- PI3K delta 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea Drug Info
VEGFR2 --- CSrc [6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-(1-methyl-1H-indol-4-yl)-amine Drug Info
Ftase --- FPTase 1-[6-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
mTOR --- PI3K gamma (3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)piperidin-4-yl)-9H-purin-2-yl)phenyl)methanol Drug Info
VEGFR2 --- CSrc isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)-3-methylphenylcarbamate Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-3-trifluoromethyl-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone Drug Info
mTOR --- PI3K gamma 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(2-chloropyridin-4-yl)urea Drug Info
VEGFR2 --- FGFR1 1-(1-tert-Butyl-1H-pyrazol-4-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea Drug Info
Ftase --- FPTase (S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-2-naphthalen-1-yl-benzoylamino)-4-methyl-pentanoic acid Drug Info
mTOR --- PI3K gamma (3-(6-morpholino-9-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-9H-purin-2-yl)phenyl)methanol Drug Info
VEGFR2 --- FGFR1 N-[2-(3-tert-Butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-N-(3-hydroxy-propyl)-acetamide Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid adamantan-1-ylamide Drug Info
mTOR --- PI3K gamma methyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino}phenyl)-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate Drug Info
VEGFR2 --- TEK SID124349961 Drug Info
Ftase --- FPTase 5-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carbonyl]-octahydro-quinoline-1-carboxylic acid amide Drug Info
NET --- SERT SID49666100 Drug Info
VEGFR2 --- TEK 7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one Drug Info
Ftase --- FPTase 1-{[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-amino}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile Drug Info
NET --- SERT (2-Chloro-phenyl)-[(3S,4R)-4-(4-chloro-phenyl)-1-methyl-pyrrolidin-3-yl]-methanone Drug Info
VEGFR2 --- TEK 5-(2-(2-aminopyrimidin-5-yl)ethynyl)-2-fluoro-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide Drug Info
Ftase --- FPTase 17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22,5.114,18.08,12.023,27]hentriaconta-1(27),8,10,14(31),15,17,20(28),21,23,25-decaen-3-one Drug Info
NPKCdelta --- NPKCtheta 4-[(4-Methyl-1H-indol-5-yl)amino]-5-{(1E)-4-[4-(phenylsulfonyl)piperazin-1-yl]but-1-en-1-yl}nicotinonitrile Drug Info
VEGFR2 --- TEK SID124350135 Drug Info
Ftase --- FPTase N-(2-Cyano-ethyl)-N-cyclopropyl-2-[2-(2-methoxy-phenyl)-1H-indol-3-yl]-acetamide Drug Info
NPKCdelta --- NPKCtheta (E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-(morpholinomethyl)pyridin-2-yl)vinyl)nicotinonitrile Drug Info
VEGFR2 --- TEK 2-(2-(4-methyl-1-piperazino)ethylamino)-5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-1Hbenzimidazole Drug Info
Ftase --- FPTase 2-[1-(3H-Imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine-4-sulfonyl]-benzoic acid methyl ester Drug Info
NPKCdelta --- NPKCtheta 5-(3,4-dimethoxyphenyl)-4-(6-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- TEK 3-(4-amino-3-{4-[3-(2-fluoro-5-trifluoromethyl-phenyl)-ureido]-phenyl}-furo[3,2-c]pyridin-7-yl)-benzenesulfonamide Drug Info
Ftase --- FPTase pentapotassium ({[(6E,10E,15E,19E)-2,6,10,16,20,24-hexamethyl-13-phosphonatopentacosa-2,6,10,15,19,23-hexaen-13-yl]phosphinato}methyl)phosphonate Drug Info
NPKCdelta --- NPKCtheta 4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidine-1-carbonyl)phenyl)thieno[2,3-b]pyridine-5-carbonitrile Drug Info

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