Multi-target agents
Target Pair | Drug Name | |
---|---|---|
MMP13 --- MMP9 | 2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-N-hydroxyacetamide | Drug Info |
Erbeta --- ER | (7S,13S,17S)-7-(4-Bromo-phenylsulfanyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,6,17-triol | Drug Info |
TRIP5 --- mRNA of KIF11 | 1-[4-[3-(4-acetyl-piperazin-1-yl)-propyl]-1-(2-fluoro-5-methyl-phenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-ethanone | Drug Info |
MMP2 --- HER2 | (5S,6S)-5-(hydroxycarbamoyl)-6-((R)-3-phenylpyrrolidine-1-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate hydrochloride | Drug Info |
Erbeta --- ER | 1-Chloro-6-(2,5-difluoro-4-hydroxy-phenyl)-naphthalen-2-ol | Drug Info |
TRIP5 --- mRNA of KIF11 | methyl 2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylate | Drug Info |
MMP2 --- MMP13 | 1-cyclopropyl-N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)phenylsulfonyl)piperidine-4-carboxamide | Drug Info |
Erbeta --- mRNA of AR | SID29216691 | Drug Info |
TRIP5 --- mRNA of KIF11 | 4-Phenyl-6-methyl-N-(4-trifluoromethylphenyl)-4,7-dihydro-2H-pyrazole[3,4-b]pyridine-5-carboxamide | Drug Info |
MMP2 --- MMP13 | (S)-N-(3,5-dimethoxybenzyl)-4-(4-((3-hydroxyquinuclidin-3-yl)ethynyl)phenoxy)benzamide | Drug Info |
Ftase --- FPTase | (S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propionylamino)-3-methyl-butyrylamino]-3-phenyl-propionylamino}-hexanoic acid | Drug Info |
TRIP5 --- mRNA of KIF11 | N-(3'-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)methanesulfonamide | Drug Info |
MMP2 --- MMP13 | N-hydroxy-4-(4-(4-(2-hydroxyphenyl)piperidin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide | Drug Info |
Ftase --- FPTase | (S)-2-Amino-1-(4-{2-[4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-3-hydroxy-propan-1-one | Drug Info |
TRIP5 --- mRNA of KIF11 | 1-(1-(3-hydroxyphenyl)-6-methyl-3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)ethanone | Drug Info |
MMP2 --- MMP13 | D-3-(1-(4-(allyloxy)benzyl)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid | Drug Info |
Ftase --- FPTase | 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid benzo[1,3]dioxol-5-ylmethyl ester | Drug Info |
TRIP5 --- mRNA of KIF11 | N-(3-aminopropyl)-N-(1-(3-benzyl-5-chloro-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)propyl)-4-methylbenzamide hydrochloride | Drug Info |
MMP2 --- MMP13 | 2-[4-(4-Bromo-benzoylamino)-benzenesulfonylamino]-6-morpholin-4-yl-hex-4-ynoic acid | Drug Info |
Ftase --- FPTase | Lithium; (S)-2-({5-[5-(4-methoxy-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate | Drug Info |
TRIP5 --- mRNA of KIF11 | rac-3-(3-hydroxyphenyl)-2-methyl-6-(pyrrolidin-1-yl)-2,3-dihydroquinazolin-4(1H)-one | Drug Info |
MMP2 --- MMP13 | N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-ylsulfonamido)-3-methylbutanamide | Drug Info |
Ftase --- FPTase | 2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(3-phenyl-propionyl)-piperazin-2-yl]-N-pyridin-3-ylmethyl-acetamide | Drug Info |
TRIP5 --- mRNA of KIF11 | O-(trityl)-L-serine | Drug Info |
MMP2 --- MMP14 | 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-3-carboxamide | Drug Info |
Ftase --- FPTase | 6-[(4-Cyano-3-naphthalen-1-yl-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-nicotinonitrile | Drug Info |
Lck --- VEGFR | N-(2,3-dihydro-1H-inden-4-yl)-4-methyl-3-(2-(methylamino)quinazolin-6-yl)benzamide | Drug Info |
MMP2 --- MMP3 | (2S,4R)-4-(3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-2-[4-(1-oxo-1,3-dihydro-isoindol-2-yl)-butyl]-6-(4-propyl-phenyl)-hexanoic acid | Drug Info |
Ftase --- FPTase | 1-{4-[3-((2R,3R)-5-tert-Butyl-2-imidazol-1-ylmethyl-2,3-dihydro-benzo[b]thiophen-3-yloxymethyl)-[1,2,4]thiadiazol-5-yl]-piperazin-1-yl}-ethanone | Drug Info |
Src --- VEGFR | N*2*,N*7*-Bis-[3-(4-methyl-piperazin-1-yl)-propyl]-3-phenyl-[1,6]naphthyridine-2,7-diamine | Drug Info |
MMP2 --- MMP3 | 2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-N-hydroxy-acetamide | Drug Info |
Ftase --- FPTase | N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)-N-(4-nitrobenzyl)quinoline-2-carboxamide | Drug Info |
VEGFR1 --- FGFR1 | 4-amino-5-(1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one | Drug Info |
MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(4'-methoxy-biphenyl-4-yl)-hexanoic acid | Drug Info |
Ftase --- FPTase | (S)-2-((S)-2-{[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyl]-methyl-amino}-3-phenyl-propionylamino)-4-hydroxy-butyric acid | Drug Info |
VEGFR2 --- Beta PDGFR | 9-Chloro-2-({3-[3-(dimethylamino)propyl]-4-fluorophenyl}-amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepine-6-thione | Drug Info |
MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(4-propyl-phenyl)-hexanoic acid | Drug Info |
Ftase --- FPTase | (S)-2-{4-[(1H-Imidazol-2-ylmethyl)-amino]-2-naphthalen-1-yl-benzoylamino}-4-methyl-pentanoic acid | Drug Info |
VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-(pyrrolidin-1-yl)ethyl)phenyl)pyrimidin-2-amine | Drug Info |
MMP2 --- MMP9 | N-hydroxy-N-(4-morpholino-1-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)butan-2-yl)formamide | Drug Info |
Ftase --- FPTase | 5-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-phenyl-prop-2-ynyl]-2'-methyl-biphenyl-2-carbonitrile | Drug Info |
VEGFR2 --- CDK1 | 4-(4-bromophenyl)-2-(4-(2-hydroxyethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
MMP2 --- MMP9 | 2-{4-[4-(4-cyano-phenyl)-piperazin-1-yl]-benzenesulfonyl}-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyric acid | Drug Info |
Ftase --- FPTase | N-Isobutyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-2-ylmethyl-acetamide | Drug Info |
VEGFR2 --- Ckit | N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-phthalazinyl)benzamide | Drug Info |
MMP2 --- MMP9 | (R)-3-(1H-Indol-3-yl)-2-(4-p-tolylethynyl-benzenesulfonylamino)-propionic acid | Drug Info |
Ftase --- FPTase | 4-(amino(1-methyl-1H-imidazol-5-yl)methyl)-2-(3-(3-ethyl-1-methyl-2-oxoazepan-3-yl)phenoxy)benzonitrile | Drug Info |
VEGFR2 --- Cmet | N1-(3-fluoro-4-(2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide | Drug Info |
MMP2 --- MMP9 | (R)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)-N-(2-morpholinoethyl)-5-(p-tolylethynyl)thiophene-2-sulfonamide | Drug Info |
Ftase --- FPTase | 6-[(3-Chloro-4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-5-(3,5-dichloro-phenyl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile | Drug Info |
Pagination
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