Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | [3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-[7-methoxy-5-(4-methyl-piperidin-1-yloxy)-quinazolin-4-yl]-amine | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 2-dimethylamino-3-(4-hydroxy-phenyl)-propyl ester | Drug Info |
| VEGFR2 --- VEGFR1 | 5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-N-m-tolyl-1,3,4-oxadiazol-2-amine | Drug Info |
| HDAC1 --- HD6 | N-Ethyl S-2-(4-acetamidophenyl)-2-oxoethyl dithiocarbamate | Drug Info |
| EGFR3 --- HER2 | 2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-quinazolin-6-yl]-acetamide | Drug Info |
| PKCA --- NPKC delta | SID103905239 | Drug Info |
| VEGFR2 --- VEGFR1 | N-(4-isopropylphenyl)-1-(2-(pyridin-4-yl)ethyl)-1H-pyrazole-5-carboxamide | Drug Info |
| HDAC1 --- HD6 | Thailandepsin A | Drug Info |
| EGFR3 --- HER2 | N4-(3-methylphenyl)-4,6-quinazolinediamine | Drug Info |
| PPAR gamma --- 5LOX | 2-(4-(3-(5,6,7,8-tetrahydronaphthalen-1-yloxy)propoxy)phenylthio)hexanoic acid | Drug Info |
| VEGFR2 --- VEGFR1 | N-(2,4-Dichloro-benzoyl)-4-fluoro-benzenesulfonamide | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-azidophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| PPAR gamma --- mRNA of PTP1B | (S)-2-[(2E,4E)-Hexadienoyl]-7-{2-[5-methyl-2-(5-methylhexyl)oxazol-4-yl]ethoxy}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid tert-butylamine salt | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(1-(3-phenylpropyl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-imidazol-1-ylmethyl-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(3-(4-(4-fluorobenzoyl)-2-propylphenoxy)propoxy)-1H-indol-1-yl)acetic acid | Drug Info |
| HDAC1 --- HDAC2 | 7-(4-(3-bromophenyl)thiazol-2-yl)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- VEGFR1 | 3-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzylamino}-propan-1-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)acetic acid | Drug Info |
| HDAC1 --- HDAC2 | 7-(4-(2,6-dimethoxyphenyl)thiazol-2-yl)-N-hydroxyheptanamide | Drug Info |
| Erbeta --- ER | 2-(3-Hydroxy-phenyl)-1-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | methyl 2-(2-methyl-4-(3-(2-propyl-4-(trifluoromethyl)phenoxy)propoxy)phenoxy)acetate | Drug Info |
| HDAC1 --- HDAC2 | 7-Phenoxy-heptanoic acid hydroxyamide | Drug Info |
| Erbeta --- ER | 2,2,2-Trichloro-1-(6-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-(5-methoxy-4-methyl-1H-indol-1-ylsulfonyl)benzamido)-5-methylbenzoic acid | Drug Info |
| HDAC1 --- HDAC2 | 4-(3-(4-(4-Chlorobenzyloxy)-3-methoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
| Erbeta --- ER | 4-{3-Ethyl-5-phenyl-4-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-furan-2-yl}-phenol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(1-{3-[4-(4-Methoxy-benzoyl)-2-propyl-phenoxy]-propyl}-1H-indol-5-yloxy)-2-methyl-propionic acid | Drug Info |
| HDAC1 --- HDAC2 | 1H-Indole-6-carboxylic acid (5-hydroxycarbamoyl-pentyl)-amide | Drug Info |
| Erbeta --- ER | [6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethylamino)-phenyl]-methanone | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(N-butyl-N-(4'-methoxy-2-methylbiphenyl-3-yl)sulfamoyl)-2,3-dimethylphenoxy)propanoic acid | Drug Info |
| HDAC1 --- HDAC4 | N-hydroxy-3-(4-(phenylsulfonamido)phenyl)acrylamide | Drug Info |
| Erbeta --- ER | 6-(3-hydroxyphenyl)naphthalen-1-ol | Drug Info |
| Erbeta --- ER | (2S,3S)-2-[4-(2-Piperidin-1-yl-ethoxy)-phenyl]-3-thiophen-2-yl-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(3-(1-(cyclohexylmethyl)-5-oxo-4-propyl-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl)phenoxy)-2-methylpropanoic acid | Drug Info |
| HER2 --- MMP-2 | (5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenylpiperidine-1-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate | Drug Info |
| Erbeta --- ER | 3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehyde oxime | Drug Info |
| PPAR gamma --- PPAR delta | (S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-4-yl)propanoic acid | Drug Info |
| JAK2 --- STK1 | SID103904525 | Drug Info |
| Erbeta --- ER | 7,9-Dihydroxy-5-oxa-11-thia-benzo[b]fluoren-10-one | Drug Info |
| PPAR gamma --- PPAR delta | {3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenoxy}-acetic acid | Drug Info |
| JNK1 --- JNK3 | 2-(2-(4-bromophenoxy)-5-(trifluoromethyl)pyridin-4-ylamino)benzamide | Drug Info |
| Erbeta --- ER | 1-(4-Fluoro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-5-ol | Drug Info |
| PPAR gamma --- PPAR delta | [2-methyl-4-(2-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl)phenoxy]acetic acid | Drug Info |
| JNK1 --- JNK3 | 2-(4-methoxyphenyl)-N-(2-(oxazol-2-yl)thiophen-3-yl)acetamide | Drug Info |
| Erbeta --- ER | (6S,6aR,10aS)-2-hydroxy-6-(4-hydroxyphenyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-8(9H)-one | Drug Info |
| PPAR gamma --- PPAR delta | 2-methyl-2-[4-{[(4-trifluoromethyl-2-[4-trifluoromethylphenyl]-thiazol-5-ylcarbonyl)amino]methyl}phenoxy]propionic acid | Drug Info |
| JNK1 --- JNK3 | 5-cyano-N-(3-methyl-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)phenyl)furan-2-carboxamide | Drug Info |
| Erbeta --- ER | [2-(4-Hydroxy-phenyl)-6-methyl-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone; hydrochloride | Drug Info |
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