Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Ftase --- FPTase | 4-[(3'-methoxy-5-nitro-biphenyl-2-ylmethoxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-benzonitrile | Drug Info |
| MMP2 --- MMP3 | 2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-biphenyl-4-yl]-piperidine-1-sulfonyl}-N-hydroxy-2-methyl-propionamide | Drug Info |
| Ftase --- FPTase | [4-Anthracen-9-yl-1-(3H-imidazol-4-ylmethyl)-1H-pyrrol-3-yl]-p-tolyl-methanone | Drug Info |
| MMP2 --- MMP3 | (R)-2-[(S)-10-Amino-1-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-decylamino]-propionic acid | Drug Info |
| Ftase --- FPTase | (S)-2-[(2'-Methyl-5-pyrimidin-5-ylethynyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid | Drug Info |
| MMP2 --- MMP3 | (R)-2-(3-biphenyl-4-yl-propyl)-N*1*-[(S)-2,2-dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-succinamide | Drug Info |
| Ftase --- FPTase | 6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-5-(3,4-dichloro-phenyl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile | Drug Info |
| MMP2 --- MMP8 | cyclooctylcarbamoylphosphonic acid | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclohepten-5-ylidene)-piperidin-1-yl]-2-(1-methyl-piperidin-4-yl)-ethanone | Drug Info |
| MMP2 --- MMP9 | 2-{4-[5-(4-Methoxy-phenyl)-thiazol-2-yl]-benzenesulfonylamino}-pentanedioic acid | Drug Info |
| Ftase --- FPTase | (S)-2-({2-[(S)-2-((R)-2-Amino-3-mercapto-propionylamino)-3-methyl-butyrylamino]-indane-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid | Drug Info |
| MMP2 --- MMP9 | (S)-N-hydroxy-2-(isopropyl(methyl)amino)-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| Ftase --- FPTase | 4-((5-((1-(4-chlorobenzyl)-2-oxopyrrolidin-3-ylamino)methyl)-1H-imidazol-1-yl)methyl)benzonitrile | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(4-cyanobenzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-butyl-N'-cyano-piperidine-1-carboxamidine | Drug Info |
| MMP2 --- MMP9 | 3-hydroxy-1-((5-(4-methoxyphenyl)thiophen-2-ylsulfonyl)methyl)pyridin-2(1H)-one | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-2-yl-ethanone | Drug Info |
| MMP2 --- MMP9 | (S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)phenylsulfonamido)propanamide | Drug Info |
| Ftase --- FPTase | 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-cyclopentanecarbonyl-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide | Drug Info |
| MMP2 --- MMP9 | (R)-5-(4-chlorophenyl)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)thiophene-2-sulfonamide | Drug Info |
| Ftase --- FPTase | 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-methoxymethyl-benzyl ester | Drug Info |
| MMP2 --- MMP9 | 4-(3-(N-hydroxyformamido)-4-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)butyl)benzoic acid | Drug Info |
| Ftase --- FPTase | (S)-2-((R)-2-((S)-2-((R)-2-amino-3-mercaptopropanamido)-3-methylbutanamido)-3-(4-hydroxy-2,3-dimethylphenyl)propanamido)-4-(methylthio)butanoic acid | Drug Info |
| MMP2 --- MMP9 | 5-(4-Benzyl-1,4-diazepan-1-yl)-5-(4-phenoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| Ftase --- FPTase | 4-((5-((1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino)methyl)-1H-imidazol-1-yl)methyl)benzonitrile | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-((4-(2-Isopropoxypyrimidin-5-yl)-5-(4-(trifluoromethoxy)-phenyl)oxazol-2-yl)methoxy)-2-methylphenoxy)acetic Acid | Drug Info |
| MMP2 --- MMP9 | (R)-4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxopiperidin-3-yl)benzenesulfonamide | Drug Info |
| Ftase --- FPTase | 10-(tert-butyl)-2,6-dimethyl-(6E,10Z)-2,6,10-dodecatriene1-diphosphate (3-tbFPP) | Drug Info |
| PR --- mRNA of AR | rac-3-(4-Nitrophenylamino)-1-(3,4-dichlorophenyl)-3-cyclohexylpropan-1-one | Drug Info |
| MMP2 --- MMP9 | (ethylamino)carbonylphosphonic acid | Drug Info |
| Ftase --- FPTase | (S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-benzoylamino]-4-methylsulfanyl-butyric acid | Drug Info |
| PR --- mRNA of AR | (Z)-5-(bromomethylene)-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | Drug Info |
| MMP3 --- MMP8 | 2-(4-Methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-methanesulfonyl-phenyl)-N'-cyano-piperidine-1-carboxamidine | Drug Info |
| PR --- mRNA of AR | (4S,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one | Drug Info |
| MMP3 --- MMP8 | 2-(4-Butoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide | Drug Info |
| Ftase --- FPTase | 4-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-(6-methyl-pyridin-3-yl)-prop-2-ynyl]-2-naphthalen-1-yl-benzonitrile | Drug Info |
| PR --- mRNA of AR | 5-(4-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene | Drug Info |
| MMP3 --- MMP8 | 2-(4-Acetylamino-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide | Drug Info |
| Ftase --- FPTase | 8-[Amino-(4-chloro-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-6-(3-chloro-phenyl)-2,3-dihydro-1-oxa-3a-aza-phenalen-4-one | Drug Info |
| PR --- mRNA of AR | racemic-4-methyl-5-(2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carbonitrile | Drug Info |
| MMP9 --- MMP8 | N-Hydroxy-N'-[(S)-2-naphthalen-2-yl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-oxalamide | Drug Info |
| Ftase --- FPTase | Lithium; (S)-2-({2'-methyl-5-[5-(4-methylsulfanyl-phenyl)-furan-2-ylmethoxymethyl]-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate | Drug Info |
| PR --- mRNA of AR | (R)-N-(3-(1-cyclopropyl-1-(2,4-difluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Cyano-5-(4-methoxyphenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| Ftase --- FPTase | 6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-3''-methoxy-biphenyl-3-carbonitrile | Drug Info |
| PR --- mRNA of AR | 4-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | Drug Info |
| mTOR --- PI3K gamma | CHEMBL592465 | Drug Info |
| Ftase --- FPTase | 5-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-biphenyl-2-carboxylic acid benzylamide | Drug Info |
| PR --- mRNA of AR | 6-(2-Phenyl-2H-imidazo[2,1-b][1,3,4]thiadiazin-3-yl)-2H-1,4-benzoxazin-3(4H)-one | Drug Info |
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