Multi-target agents

Target Pair Drug Name
HDAC1 --- HDAC2 8-[5-(4-Methoxy-phenyl)-oxazol-2-yl]-2-oxo-octanoic acid methylamide Drug Info
VEGFR2 --- CSrc 2,6-dimethylphenyl-2,4-bis(methyloxy)phenyl(2-((4-((3-(1-piperidinyl)propyl)oxy)phenyl)amino)-4-pyrimidinyl)carbamate Drug Info
EGFR3 --- VEGFR1 2-(Methyl-{4-[7-(2-methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-amino)-ethanol Drug Info
PPAR gamma --- PPAR delta (S)-3-(4-(3,3-bis(4-methoxyphenyl)allyloxy)phenyl)-2-ethoxypropanoic acid Drug Info
HDAC1 --- HDAC2 2-Oxo-nonanedioic acid 1-methylamide 9-quinolin-3-ylamide Drug Info
VEGFR2 --- EGFR3 methyl 4-(6,7-dimethoxyquinazolin-4-ylamino)phenylcarbamate Drug Info
Erbeta --- ER 2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-6-ol Drug Info
PPAR gamma --- PPAR delta (1'S*,5'R*)-6-(5-Heptyl-2-Iodo-4-oxocyclopent-2-enyloxy)hexanoic Acid Drug Info
HDAC1 --- HDAC2 7-(2-(4-fluorophenyl)oxazol-5-yl)-N-hydroxyheptanamide Drug Info
VEGFR2 --- FGFR1 CHEMBL1762527 Drug Info
Erbeta --- ER 1-(2-{4-[8-Fluoro-4-(4-fluorophenyl)-2,3-dihydro-benzo[b]-oxepin-5-yl]-phenoxy}-ethyl)-pyrrolidine Drug Info
PPAR gamma --- PPAR delta 2-(6-(3-(4-(4-fluorobenzoyl)phenoxy)propoxy)-1H-indol-1-yl)acetic acid Drug Info
HDAC1 --- HDAC2 N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide Drug Info
VEGFR2 --- TEK 1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea Drug Info
Erbeta --- ER 9a-(4-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Drug Info
PPAR gamma --- PPAR delta (+/-)-2-{5-[(4-Adamantan-1-yl-benzoylamino)-methyl]-2-fluoro-4-methoxy-benzyl}-butyric acid Drug Info
HDAC1 --- HDAC4 (S)-tert-butyl 1-(tert-butylamino)-7-mercapto-1-oxoheptan-2-ylcarbamate Drug Info
VEGFR2 --- TEK 1-(2-chlorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea Drug Info
Erbeta --- ER 3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-benzo[1,4]oxathiin-6-ol Drug Info
PPAR gamma --- PPAR delta 2-(3-chloro-4-(3-(3-phenyl-7-propylbenzofuran-6-yloxy)propylthio)phenyl)acetic acid Drug Info
HDAC1 --- HDAC4 (S)-tert-butyl 7-mercapto-1-oxo-1-(quinolin-3-ylamino)heptan-2-ylcarbamate Drug Info
VEGFR2 --- TEK 2-methyl-3-(5-methyl-3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide Drug Info
Erbeta --- ER (R)-9a-ethyl-6-(trifluoromethyl)-9,9a-dihydroindeno[2,1-e]indazole-7,10(3H,8H)-dione Drug Info
PPAR gamma --- PPAR delta 2-(5-(2-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)ethoxy)-1H-indol-1-yl)acetic acid Drug Info
HER2 --- MMP-1 (5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate Drug Info
VEGFR2 --- TEK 1-(4-methoxyphenyl)-3-[19-methyl-3-(2-methylpropyl)-14-oxo-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl]urea Drug Info
Erbeta --- ER 6-(4-Hydroxy-phenyl)-1-nitro-naphthalen-2-ol Drug Info
PPAR gamma --- PPAR delta {4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid Drug Info
DHODH --- IL17 SID174007069 Drug Info
VEGFR2 --- TEK 1-(4-chlorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea Drug Info
Erbeta --- ER 3-Bromo-4,6-dihydroxy-2-(4-hydroxy-phenyl)-inden-1-one Drug Info
PPAR gamma --- PPAR delta (S)-5-(3-(3-(4-(cyclohexylidenemethyl)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione Drug Info
JNK1 --- JNK3 SID103905193 Drug Info
VEGFR2 --- TEK methyl N-(5-(4-((2-chloro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-1H-benzimidazol-2-yl)carbamate Drug Info
Erbeta --- ER 5,7-dihydroxy-3-(2-fluoro-4-hydroxyphenyl)-4(3H)-quinazolinone Drug Info
PPAR gamma --- PPAR delta 2-(4-{2-[1-(2-Biphenyl-4-yl-ethyl)-3-cyclohexyl-ureido]-ethyl}-phenylsulfanyl)-2-methyl-propionic acid Drug Info
JNK1 --- JNK3 4-(naphthalen-2-yl)-3-(2-(pyridin-3-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one Drug Info
VEGFR2 --- TEK 4-Amino-7-cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid amide Drug Info
Erbeta --- ER (2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[(6R,7S)-2-(octahydro-isoindol-2-yl)-ethoxy]-phenyl}-2,3-dihydro-benzo[1,4]oxathiin-6-ol Drug Info
PPAR gamma --- PPAR delta rac-2-(4-Methoxy-3-((4-phenethoxybenzamido)methyl)benzyl)butanoic acid Drug Info
JNK1 --- JNK3 N-(4-bromo-3-(1-methyl-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydro-1,5-naphthyridin-1(2H)-yl)acetamide Drug Info
VEGFR2 --- VEGFR1 (5-Ethanesulfonyl-2-methoxy-phenyl)-[5-(4-fluoro-phenyl)-oxazol-2-yl]-amine Drug Info
Erbeta --- ER 1-Ethyl-2-(4-hydroxy-phenyl)-pyrrolo[2,1,5-cd]indolizin-6-ol Drug Info
PPAR gamma --- PPAR delta (R)-2-(4-methoxy-3-(4-(trifluoromethyl)benzylcarbamoyl)benzyl)butanoic acid Drug Info
JNK1 --- JNK3 4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)-1H-1,2,4-triazol-5(4H)-one Drug Info
VEGFR2 --- VEGFR1 N-(2,4-Dichloro-benzoyl)-3-methyl-benzenesulfonamide Drug Info
Erbeta --- ER 4-[2-(4-hydroxyphenyl)-1-{6-methyl[3-(4,4,5,5,5-pentafluoropentylsulfanyl)propyl]aminohexyl}-(E)-1-butenyl]phenol Drug Info
PPAR gamma --- PPAR delta (S)-3-(4-(2-(2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-methoxypropanoic acid Drug Info
JNK1 --- JNK3 N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide Drug Info
VEGFR2 --- VEGFR1 (1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quinolin-4-ylmethyl)benzenamine Drug Info

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